- Path:
-
The diagnostic performance of machine learning-based FFRCT for coronary artery disease: A meta-analysis
Files
External resources
Periodical
- Title:
- Open medicine
- Publication:
-
Berlin: de Gruyter
- Note:
- Open Access
- Namensnennung 4.0 International
- Scope:
- Online-Ressource
- ISSN:
- 2391-5463
- ZDB-ID:
-
2829380-0
- VÖBB-Katalog:
- 35318930
- Keywords:
- Zeitschrift
- DDC Group:
- 610 Medizin
- Collection:
- Medizin
- Copyright:
- Rights reserved
- Accessibility:
- Free Access
- Title:
- Open medicine
- Publication:
-
Berlin: de Gruyter
- Note:
- Open Access
- Namensnennung 4.0 International
- Scope:
- Online-Ressource
- ISSN:
- 2391-5463
- ZDB-ID:
-
2829380-0
- VÖBB-Katalog:
- 35318930
- Keywords:
- Zeitschrift
- DDC Group:
- 610 Medizin
- Collection:
- Medizin
- Copyright:
- Rights reserved
- Accessibility:
- Free Access
Article
- Title:
- The diagnostic performance of machine learning-based FFRCT for coronary artery disease: A meta-analysis
- Publication:
-
Berlin: de Gruyter, 2025
- Language:
- English
- Information:
- Background: This meta-analysis evaluates the diagnostic accuracy of machine learning-derived FFRCT (ML-FFRCT) for CAD, using invasive coronary angiography-derived fractional flow reserve (ICA-FFR) as the gold standard to provide evidence for clinical translation. Methods: We systematically searched PubMed and Embase for relevant studies. Study quality was assessed using QUADAS-2 in RevMan 5.3. Diagnostic performance was evaluated by pooling sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and the area under the curve (AUC) using Stata 14.0. Meta-regression and subgroup analyses were conducted based on the publication year, country, study design, sample source, and sample size. Results: The pooled SEN was 0.84 (95% CI: 0.79–0.87) and SPE was 0.83 (95% CI: 0.77–0.88). The PLR and NLR were 4.95 (95% CI: 3.58–6.84) and 0.20 (95% CI: 0.15–0.26), respectively. The DOR was 25.15 (95% CI: 14.87–42.52) and the AUC was 0.90 (95% CI: 0.87–0.93), indicating high diagnostic accuracy. Deeks’ funnel plot revealed no significant publication bias. Conclusions: ML-FFRCT demonstrates high SEN and SPE in diagnosing CAD. These findings support its potential as a promising noninvasive tool for CAD assessment.
- Scope:
- Online-Ressource
- Note:
- Open Access
- Archivierung/Langzeitarchivierung gewährleistet
- Keywords:
- machine learning ; FFRCT ; CAD ; meta
- Classification:
- Medizin
- Collection:
- Medizin
- Copyright:
- CC BY
- Accessibility:
- Free Access
- Title:
- The diagnostic performance of machine learning-based FFRCT for coronary artery disease: A meta-analysis
- Publication:
-
Berlin: de Gruyter, 2025
- Language:
- English
- Information:
- Background: This meta-analysis evaluates the diagnostic accuracy of machine learning-derived FFRCT (ML-FFRCT) for CAD, using invasive coronary angiography-derived fractional flow reserve (ICA-FFR) as the gold standard to provide evidence for clinical translation. Methods: We systematically searched PubMed and Embase for relevant studies. Study quality was assessed using QUADAS-2 in RevMan 5.3. Diagnostic performance was evaluated by pooling sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and the area under the curve (AUC) using Stata 14.0. Meta-regression and subgroup analyses were conducted based on the publication year, country, study design, sample source, and sample size. Results: The pooled SEN was 0.84 (95% CI: 0.79–0.87) and SPE was 0.83 (95% CI: 0.77–0.88). The PLR and NLR were 4.95 (95% CI: 3.58–6.84) and 0.20 (95% CI: 0.15–0.26), respectively. The DOR was 25.15 (95% CI: 14.87–42.52) and the AUC was 0.90 (95% CI: 0.87–0.93), indicating high diagnostic accuracy. Deeks’ funnel plot revealed no significant publication bias. Conclusions: ML-FFRCT demonstrates high SEN and SPE in diagnosing CAD. These findings support its potential as a promising noninvasive tool for CAD assessment.
- Scope:
- Online-Ressource
- Note:
- Open Access
- Archivierung/Langzeitarchivierung gewährleistet
- Keywords:
- machine learning ; FFRCT ; CAD ; meta
- Classification:
- Medizin
- Collection:
- Medizin
- Copyright:
- CC BY
- Accessibility:
- Free Access
