The journal of pediatric endocrinology and metabolism: Reninoma: an unusual cause of growth failure

Vaghasia, Nupoor; Jevalikar, Ganesh; Kuchay, Mohammad Shafi; Lipi, Lipika; Mithal, Ambrish

Images of Writing in the Qurʾān and Sulṭān as a Royal Warrant / Stewart, Devin J. (Rights reserved)

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Contents : Images of Writing in the Qurʾān and Sulṭān as a Royal Warrant / Stewart, Devin J. (Rights reserved)

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Eingeschränkter Zugang mit Nutzungsbeschränkungen: Das Dokument ist in den Räumen der Zentral- und Landesbibliothek mit dem "Virtuellen Lesesaal der Landesbibliothek" auf allen Internet-Arbeitsplätzen zugreifbar, darf jedoch nicht kopiert, versendet oder in einem Umfang von mehr als 10% ausgedruckt werden. Weitere Informationen.

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Periodical

Title:: The journal of pediatric endocrinology and metabolism

Publication:: Berlin [u.a.]: de Gruyter

Scope:: Online-Ressource

ISSN:: 2191-0251

ZDB-ID:: 2583847-7

VÖBB-Katalog:: 15261592

Keywords:: Zeitschrift

Classification:: Medizin

Collection:: Medizin

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Title:: The journal of pediatric endocrinology and metabolism

Publication:: Berlin [u.a.]: de Gruyter

Scope:: Online-Ressource

ISSN:: 2191-0251

ZDB-ID:: 2583847-7

VÖBB-Katalog:: 15261592

Keywords:: Zeitschrift

Classification:: Medizin

Collection:: Medizin

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Article

Author:: Vaghasia, Nupoor; Jevalikar, Ganesh; Kuchay, Mohammad Shafi; Lipi, Lipika; Mithal, Ambrish

Title:: Reninoma: an unusual cause of growth failure

Publication:: Berlin [u.a.]: de Gruyter, 2025

Language:: English

Information:: Objectives: Growth failure can result from various underlying causes, necessitating a thorough evaluation. Reninoma, a rare renin-secreting tumor, is an uncommon cause of hypertension, especially in paediatric patients, and has not been associated with growth failure until now. Case presentation: An 11-year-old girl presented with complaints of poor height gain, headaches, increased thirst, and vomiting. The evaluation revealed severe hypertension and hypokalemic alkalosis. Investigations indicated renin-dependent hypertension, and imaging identified a right renal mass. Renal venous sampling confirmed renin production from the tumor. A right open partial nephrectomy was performed, resulting in the normalization of blood pressure and improved growth. Over the following years, she achieved a significant catch-up growth, regaining her original height percentile and the target adult height. Conclusions: This case adds to the limited literature on paediatric reninoma. It highlights a rare presentation of reninoma causing hypertension and growth failure in a child. The growth failure was likely due to hypokalemic alkalosis-induced low insulin-like growth factor 1 (IGF-1) levels, a mechanism not previously documented in paediatric reninoma cases. Surgical excision of the tumor led to normalization of blood pressure and metabolic alkalosis with significant growth recovery.

Scope:: Online-Ressource

Note:: Kein Open Access; Archivierung/Langzeitarchivierung gewährleistet

Keywords:: growth failure ; growth velocity ; pediatric hypertension ; reninoma

Classification:: Medizin; Sonstiges

URN:: urn:nbn:de:101:1-2501120255159.516025113992

Collection:: Medizin; Sonstiges

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Author:: Vaghasia, Nupoor; Jevalikar, Ganesh; Kuchay, Mohammad Shafi; Lipi, Lipika; Mithal, Ambrish

Title:: Reninoma: an unusual cause of growth failure

Publication:: Berlin [u.a.]: de Gruyter, 2025

Language:: English

Information:: Objectives: Growth failure can result from various underlying causes, necessitating a thorough evaluation. Reninoma, a rare renin-secreting tumor, is an uncommon cause of hypertension, especially in paediatric patients, and has not been associated with growth failure until now. Case presentation: An 11-year-old girl presented with complaints of poor height gain, headaches, increased thirst, and vomiting. The evaluation revealed severe hypertension and hypokalemic alkalosis. Investigations indicated renin-dependent hypertension, and imaging identified a right renal mass. Renal venous sampling confirmed renin production from the tumor. A right open partial nephrectomy was performed, resulting in the normalization of blood pressure and improved growth. Over the following years, she achieved a significant catch-up growth, regaining her original height percentile and the target adult height. Conclusions: This case adds to the limited literature on paediatric reninoma. It highlights a rare presentation of reninoma causing hypertension and growth failure in a child. The growth failure was likely due to hypokalemic alkalosis-induced low insulin-like growth factor 1 (IGF-1) levels, a mechanism not previously documented in paediatric reninoma cases. Surgical excision of the tumor led to normalization of blood pressure and metabolic alkalosis with significant growth recovery.

Scope:: Online-Ressource

Note:: Kein Open Access; Archivierung/Langzeitarchivierung gewährleistet

Keywords:: growth failure ; growth velocity ; pediatric hypertension ; reninoma

Classification:: Medizin; Sonstiges

URN:: urn:nbn:de:101:1-2501120255159.516025113992

Collection:: Medizin; Sonstiges

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Access restriction

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