Open medicine: Correlation between fat-soluble vitamin levels and inflammatory factors in paediatric community-acquired pneumonia: A prospective study

Liao, Jianyuan; Zhang, Lifang; Chen, Gangxin; Luo, Yuxing

Correlation between fat-soluble vitamin levels and inflammatory factors in paediatric community-acquired pneumonia: A prospective study / Liao, Jianyuan (CC BY)

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fullscreen: Correlation between fat-soluble vitamin levels and inflammatory factors in paediatric community-acquired pneumonia: A prospective study / Liao, Jianyuan (CC BY)

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Freier Zugang: Das Werk ist uneingeschränkt verfügbar.

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CC BY: Namensnennung 4.0 International. Weitere Informationen finden Sie hier.

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Titel:: Open medicine

Erschienen:: Berlin: de Gruyter

Fußnote:: Open Access; Namensnennung 4.0 International

Umfang:: Online-Ressource

ISSN:: 2391-5463

ZDB-ID:: 2829380-0

VÖBB-Katalog:: 35318930

Schlagworte:: Zeitschrift

Dewey-Dezimalklassifikation:: 610 Medizin

Copyright:: Rechte vorbehalten

Zugriffsberechtigung:: Freier Zugang

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Verfasser:: Liao, Jianyuan; Zhang, Lifang; Chen, Gangxin; Luo, Yuxing

Titel:: Correlation between fat-soluble vitamin levels and inflammatory factors in paediatric community-acquired pneumonia: A prospective study

Erschienen:: Berlin: de Gruyter, 2024

Sprache:: Englisch

Zusammenfassung:: Abstract: Community-acquired pneumonia (CAP) is a common respiratory disease in children. This prospective cohort study of 110 children with CAP and 100 healthy children investigated the relationship between the levels of vitamin A, D and E and inflammatory markers, such as tumour necrosis factor (TNF-a), interleukin-1 (IL-1), interleukin-10 (IL-10), neutrophils (NE) and C-reactive protein (CRP), in CAP. The haemoglobin, leukocyte concentration, NE, monocytes and CRP concentration in the CAP group showed significant differences (P < 0.05). The levels of vitamin A, D and E in the CAP group were lower than those in the control group, while the levels of TNF-a and IL-1 were higher than in the control group; the differences were statistically significant (P < 0.05). The IL-10 levels showed no significant differences (P > 0.05). Pearson analysis revealed that the vitamin A, D and E levels were all correlated with the TNF-a, IL-10 and CRP levels (P < 0.05). The vitamin A, D and E levels of the CAP children were lower than those of the healthy children. Thus, the content of fat-soluble vitamins is correlated with the secretion of TNF-a and IL-10. The research provides a new direction for the prevention, diagnosis and treatment of CAP.

Umfang:: Online-Ressource

Fußnote:: Open Access; Archivierung/Langzeitarchivierung gewährleistet

Schlagworte:: paediatric CAP ; fat-soluble vitamins ; TNF-a ; IL-1 ; IL-10

ZLB-Systematik:: Medizin; Sonstiges

URN:: urn:nbn:de:101:1-2406081536379.065320346830

Sammlung:: Medizin; Sonstiges

Copyright:: CC BY

Zugriffsberechtigung:: Freier Zugang

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