Sigma Metrics misconceptions and limitations / Duan, Xincen (Rights reserved)

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Zugriffsbeschränkung

Eingeschränkter Zugang mit Nutzungsbeschränkungen: Das Dokument ist in den Räumen der Zentral- und Landesbibliothek mit dem "Virtuellen Lesesaal der Landesbibliothek" auf allen Internet-Arbeitsplätzen zugreifbar, darf jedoch nicht kopiert, versendet oder in einem Umfang von mehr als 10% ausgedruckt werden. Weitere Informationen.

Nutzungslizenz

Keine Nutzungslizenz vergeben - es gilt das deutsche Urheberrecht: Mit dieser Kennzeichnung versehene Werke unterliegen dem deutschen Urheberrecht. Sie dürfen diese nur mit ausdrücklicher und schriftlicher Genehmigung des Urhebers/Rechteinhabers bzw. der Urheberin/Rechteinhaberin weiterverwenden oder vervielfältigen. Sie sind für die Einhaltung der Rechtsvorschriften selbst verantwortlich und kÃ¶nnen bei Missbrauch haftbar gemacht werden. Diese Kennzeichnung wird vorsorglich auch bei Werken verwendet, bei denen die Gemeinfreiheit nicht zweifelsfrei festgestellt werden konnte. Weitere Informationen finden Sie in den Nutzungshinweisen.

Zeitschrift

Urheber (Körperschaft):: Charlottenburg

Titel:: Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten der Stadt Charlottenburg : für das Verwaltungsjahr ... / bearbeitet im Statistischen Amt

Weitere Titel:: Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten für das Etatsjahr ...; Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten des Stadtkreises Charlottenburg

Erschienen:: Charlottenburg 1922

Digitalisierung:: Berlin: Zentral- und Landesbibliothek Berlin, 2017

Erscheinungsverlauf:: 1879/80-1915/1920

ZDB-ID:: 2900353-2

Berlin:: B 770 Staat. Politik. Verwaltung: Bezirksbehörden

Dewey-Dezimalklassifikation:: 350 Öffentliche Verwaltung

Sammlung:: Staat, Politik, Verwaltung, Recht

Copyright:: Public Domain / Gemeinfrei

Zugriffsberechtigung:: Freier Zugang

Urheber (Körperschaft):: Charlottenburg

Titel:: Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten der Stadt Charlottenburg : für das Verwaltungsjahr ... / bearbeitet im Statistischen Amt

Weitere Titel:: Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten für das Etatsjahr ...; Bericht über die Verwaltung und den Stand der Gemeindeangelegenheiten des Stadtkreises Charlottenburg

Erschienen:: Charlottenburg 1922

Digitalisierung:: Berlin: Zentral- und Landesbibliothek Berlin, 2017

Erscheinungsverlauf:: 1879/80-1915/1920

ZDB-ID:: 2900353-2

Berlin:: B 770 Staat. Politik. Verwaltung: Bezirksbehörden

Dewey-Dezimalklassifikation:: 350 Öffentliche Verwaltung

Sammlung:: Staat, Politik, Verwaltung, Recht

Copyright:: Public Domain / Gemeinfrei

Zugriffsberechtigung:: Freier Zugang

Band

Erschienen:: 1895

Sprache:: Deutsch

Digitalisierung:: Berlin: Zentral- und Landesbibliothek Berlin, 2017

Berlin:: B 770 Staat. Politik. Verwaltung: Bezirksbehörden

Dewey-Dezimalklassifikation:: 350 Öffentliche Verwaltung

URN:: urn:nbn:de:kobv:109-1-10439614

Standort der Druckausgabe:: Zentral- und Landesbibliothek Berlin

Copyright:: Public Domain / Gemeinfrei

Zugriffsberechtigung:: Freier Zugang

Sammlung:: Staat, Politik, Verwaltung, Recht

Erschienen:: 1895

Sprache:: Deutsch

Digitalisierung:: Berlin: Zentral- und Landesbibliothek Berlin, 2017

Berlin:: B 770 Staat. Politik. Verwaltung: Bezirksbehörden

Dewey-Dezimalklassifikation:: 350 Öffentliche Verwaltung

URN:: urn:nbn:de:kobv:109-1-10439614

Standort der Druckausgabe:: Zentral- und Landesbibliothek Berlin

Copyright:: Public Domain / Gemeinfrei

Zugriffsberechtigung:: Freier Zugang

Sammlung:: Staat, Politik, Verwaltung, Recht

Kapitel

Titel:: Text

Titel:: Text

Schnellzugriff

Clinical chemistry and laboratory medicine (Rights reserved)
Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe / Dugues, Paméla (Rights reserved)
The ARRplus: a model for renin-dependent and sex-specific aldosterone cut-offs that improves screening for primary aldosteronism / Fuld, Sybille (CC BY)
Laboratory findings in patients treated with complement factor C3 inhibitor pegcetacoplan / Langemeijer, Saskia M.C. (CC BY)
Utility of flow cytometric PAX5 protein detection for the diagnosis of B-cell acute lymphoblastic leukemia / Pootrakul, Tanintorn (Rights reserved)
Establishment of allowable total error for semen analysis based on the state of the art in China / Zheng, Yan (Rights reserved)
Analytical performance of an automated LC-MS/MS analyzer for determination of vitamin D concentration in blood plasma and serum / Weaver, Katie (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of testosterone in human serum and plasma / Fux, Elie (Rights reserved)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 17-hydroxyprogesterone in human serum and plasma / Bachmann, Martina (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of linezolid in human serum and plasma / Kubicova, Marie (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of voriconazole in human serum and plasma / Kubicova, Marie (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma / Lewin, Lea (CC BY)
Validation study of the Helena V8 UltraCE capillary elecrophoresis analyser / Delanghe, Joris (CC BY)
Comparison of six serum analyte workflows using routine liquid chromatography-tandem mass spectrometry methods at multiple laboratories with the Cobas i 601 analyzer, an automated mass spectrometry system / Vermeersch, Pieter (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma / Ibrahim, Sara Cheikh (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisol in human urine / Ott, Myriam (CC BY)
Result harmonization in medical laboratories: accomplishments and challenges / Badrick, Tony (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of progesterone in human serum and plasma / Ibrahim, Sara Cheikh (CC BY)
An isotope dilution-liquid chromatography tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone in human serum and plasma / Lewin, Lea (CC BY)
An isotope dilution-liquid-chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of total and free valproic acid in human serum and plasma / Schierscher, Tobias (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of mycophenolic acid glucuronide in human serum and plasma / Schierscher, Tobias (CC BY)
An isotope dilution-liquid-chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of mycophenolic acid in human serum and plasma / Schierscher, Tobias (CC BY)
Comparability, compatibility, equivalence and interchangeability: metrological concepts widely misunderstood in laboratory medicine / Rigo-Bonnin, Raúl (Rights reserved)
Applying the Implementation Science to the harmonization of laboratory test results in the changing landscape / Panteghini, Mauro (CC BY)
Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes / Gruson, Damien (Rights reserved)
T-cell receptor beta constant 1 flow cytometry for diagnosing clonality in mature T-cell neoplasms: a systematic review and meta-analysis of diagnostic accuracy / Biaggioni, Pablo Adrian (Rights reserved)
Metrological traceability enters the boardroom of IVD-manufacturers / Cobbaert, Christa (CC BY)
Falsely elevated serum estradiol levels measured by Abbott estradiol immunoassay in women taking abemaciclib / Lapić, Ivana (Rights reserved)
Machine learning in precision oncology: a rough diamond waiting to shine? / De Bruyne, Sander (Rights reserved)
Holiday-associated biochemical patterns of pancreatitis: a 16-year retrospective analysis of ambulatory laboratory data (2009–2024) / Hollenstein, Marlene (Rights reserved)
Cryoproteins: a rare cryofibrinogenemia case / Maseti, Ann Amvuyele (CC BY)
Cytoplasmic crystalline inclusions in lymphocytes of B-cell lymphoproliferative disorders / Balan, Mirela (Rights reserved)
Experimental evaluation of colorimetric beverage drug tests: reliability and limitations / Di Trana, Annagiulia (Rights reserved)
Hyperferritinemia and analytical challenges: can proteomics make the difference? / Corasolla Carregari, Victor (Rights reserved)
Frontmatter (Rights reserved)
Antiphosphatidylserine/prothrombin antibodies define a high-risk antiphospholipid syndrome profile associated with organ damage / Hoxha, Ariela (CC BY)
Personalized reference intervals based on biological variation for serum bone turnover markers in healthy older adults / Qin, Ye (Rights reserved)
Measurement of lipoprotein (a) via a novel point of care approach with comparison to established laboratory assays / Bachmeier, Caroline A.E. (CC BY)
Cardiac troponin T measurement following cardiac surgery in children with congenital heart defects predicts adverse outcomes / Isgrò, Giuseppe (Rights reserved)
Laboratory solution to diagnose and monitor atypical IgG4-mediated anti-GBM disease / Jacobs, Joannes F.M. (CC BY)
Optimizing diagnostic thresholds of total vitamin B12 (B12) for identifying cobalamin deficiency in adults with macrocytic anemia / Pelloso, Michela (Rights reserved)
Evaluation of the MAGLUMI non-competitive angiotensin I chemiluminescence immunoassay for measuring renin activity in human plasma / Wu, Lina (Rights reserved)
Biological variation and inter-relation between key calcium homeostasis biomarkers / Guldhaug, Nora Alicia (CC BY)
Kappa Index predicts disease activity and transition to high-efficacy therapies in multiple sclerosis / Marcheselli, Simone (Rights reserved)
Serum GFAP as a biomarker for progression in multiple sclerosis: assay comparison and a large reference database of healthy controls / Willemse, Eline A.J. (Rights reserved)
Development and validation of a candidate reference measurement procedure for free triiodothyronine and free thyroxine in human serum using equilibrium dialysis isotope-dilution liquid chromatography-tandem mass spectrometry / Zhan, Min (Rights reserved)
From ordering to interpretation: a comprehensive framework for laboratory test indications / Weninger, Jasmin (Rights reserved)
On the cusp of global lipoprotein (a) standardization / Cobbaert, Christa (CC BY)
Green laboratory through test ordering appropriateness and innovation / Stangalini, Sveva (Rights reserved)
From venipuncture to self-sampling dried blood spots: a shift in monitoring testosterone levels / Olthof, Anouk (CC BY)
Serial measurements of neuron specific enolase, glial fibrillary acidic protein and neurofilament light for mortality prediction in patients with severe acute brain injury in the ICU / Haksteen, Wolmet E. (CC BY)
Quantitative analysis of phylloquinone (vitamin K1) and menaquinone (vitamin K2) in serum of Russians by liquid chromatography-tandem mass spectrometry / Vokuev, Mikhail (Rights reserved)
Analytical and diagnostic evaluation of the Anvajo fluidlab 2 analyzer: a novel urine particle analyzer for clinical application using digital holographic microscopy? / Deprez, Sigrid (Rights reserved)
The democratization of cancer screening, or a waste of valuable resources? / Chatanaka, Miyo K. (Rights reserved)
From automation to agentic artificial intelligence in laboratory medicine: an opinion of the IFCC Division on Emerging Technologies / Gruson, Damien (Rights reserved)
From conventional to personalized reference intervals and decision limits: addressing latent errors in the post-post analytical phase / Coskun, Abdurrahman (Rights reserved)
Blood biomarkers in neurodegenerative diseases: pre-analytical, analytical, and post-analytical challenges / Delaby, Constance (CC BY)
Optimising lipoprotein (a) tests: we are almost there / Langlois, Michel R. (Rights reserved)
Hook effect for ferritin immunoassays: implications for clinical practice / Asare-Werehene, Meshach (Rights reserved)
The hook effect of an immunoassay results in a series of pediatric patients with elevated total immunoglobulin E: implications for dilution protocols and method comparison / Melnichuk, Oleg (Rights reserved)
The indispensable role of phenotypic screening in thalassemia diagnosis: a case of deception uncovered by inconsistent results / Li, Youqiong (Rights reserved)
Defining non-diabetic hypoglycemia: is there an appropriate plasma glucose threshold? / González-Vidal, Tomás (Rights reserved)
Cortisol measurement challenges in managing ectopic Cushing’s syndrome with etomidate / Brouwers, Pauline (Rights reserved)
Toward neonatal analytical stewardship: building on Cadamuro et al.’s minimum-volume framework / Vijayasimha, Mulavagili (Rights reserved)
Response to Lenters-Westra, Erna, et al. “Limitations of glycated albumin standardization when applied to the assessment of diabetes patients” Clin Chem Lab Med doi.org/10.1515/cclm-2024-0591 / Sherfan, Julie (Rights reserved)
Frontmatter (Rights reserved)
Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature / Sanz-Felisi, María (Rights reserved)
One copy in one-pot for rapid and accurate SFTSV testing by LAC12b-2M / Pang, Ya (Rights reserved)
Contribution of SuPAR for patients in a situation of uncertainty downstream of emergencies / Brailova, Marina (Rights reserved)
Prognostic value of suPAR in sepsis: a potential tool to support patient management in the Emergency Department / Leggeri, Simone (Rights reserved)
Performance evaluation of a new high-sensitivity cardiac troponin T assay: hs-cTnT (CLIA) assay / Shu, Xin (Rights reserved)
Extended verification of an automated MALDI-TOF mass spectrometry system for high throughput serum M-protein measurement / Nevejan, Louis (Rights reserved)
Analytical verification and comparative assessment of the new Atellica IM high-sensitivity prostate specific antigen assay / Filella, Xavier (Rights reserved)
Assessment for potential bias in multiplexed IL-10 and TNF-α from plex count / Sanders, Wade M. (CC BY)
A specific-neonatal hemolysis correction model for accurate potassium assessment in blood samples with in vitro hemolysis / Li, Jinmei (Rights reserved)
Comparative analysis of three platforms for serum NfL quantification in healthy controls and MS patients / Dargvainiene, Justina (CC BY)
Uracil in plasma: comparison of two in-house-developed LC-MS/MS methods / Hansen, Svend H. (CC BY)
Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D: from lab sampling to home sampling / Heughebaert, Liesl (Rights reserved)
At-home blood collection for clinical chemistry analyses in a kidney transplant population: a feasibility study / Hoekstra, Jorrit (CC BY)
Comparison of blood sample quality and test results between robotic and manual venipuncture: a pilot study / Wang, Rong (CC BY)
Implementation of an automated alert system of critical results in hospitalized and emergency patients / García-de la Torre, Angela (Rights reserved)
Impact of an autonomous delivery robot on sample turnaround time in a clinical laboratory: an early evaluation of first implementation / Gervasoni, Jacopo (Rights reserved)
Assessment of drone transport for biological samples: a real-world experience at a tertiary hospital / Calomarde-Pastor, Paula (CC BY)
Addressing the silent epidemic of recreational nitrous oxide use: a position, call to action and recommendations by the European Federation of Clinical Chemistry and Laboratory Medicine Committee on Biological Markers of Nitrous Oxide Abuse / Grzych, Guillaume (Rights reserved)
Recommendations from the IFCC Working Group on Laboratory Errors and Patient Safety for the Global Adoption of an Essential Quality Indicators Panel in Laboratory Medicine / De Guire, Vincent (Rights reserved)
Science, Quality and Value of Laboratory Medicine / Plebani, Mario (CC BY)
Reimagining External Quality Assessment for precision medicine: a perspective from biochemistry laboratories / Chigaro, Stanford (Rights reserved)
Hierarchy of reference interval models: advancing laboratory data interpretation / Streichert, Thomas (Rights reserved)
Artificial intelligence and machine learning in thrombosis and hemostasis: a scoping review of clinical and laboratory applications, challenges, and future directions / Altememi, Mohammad A. (Rights reserved)
Capillary blood in core laboratories: current and future challenges / González, Álvaro (Rights reserved)
Reshaping laboratory medicine through technological advances / Lippi, Giuseppe (Rights reserved)
A study of the performance of different methods for measuring serum lithium / Fan, Xiaoyu (Rights reserved)
Mass spectrometry reveals limitations of serum immunofixation electrophoresis in monitoring lambda light chain myeloma / Chen, Yu (Rights reserved)
Spun citrate samples as a suitable alternative for platelet measurement. Is recollection necessary? A preliminary study / Nikler, Ana (Rights reserved)
Innovative closed tube protocol reveals a super critical early preanalytical phase of whole blood glucose stability in routine matrices / Grzych, Guillaume (Rights reserved)
Response to: Shift happens: The utility of external quality assessment data in evaluating folate lot changes. doi.org/10.1515/cclm-2025-1569 / Larsson, Anders (CC BY)
Shift happens: the utility of external quality assessment data in evaluating folate lot changes / Marrington, Rachel (CC BY)
47 th Annual Conference of the Association for Clinical Biochemists in Ireland (ACBI) (Rights reserved)
Comparative analysis of plasma p-tau217 immunoassays: challenges for standardization and harmonization / Arslan, Burak (CC BY)
Combining the calibrator uncertainty and the long-term measurement uncertainty? A comment to the ISO/TS 20914 guideline / Åsberg, Arne (Rights reserved)
Frontmatter (Rights reserved)
Prognostic utility of serial procalcitonin measurements in ICU sepsis: a laboratory-led modelling approach in a resource-limited setting procalcitonin modelling for sepsis mortality in a low-resource ICU / Fataar, Aaqilah (Rights reserved)
Pro-gastrin releasing peptide as a tumor marker of medullary thyroid carcinoma: a comparative bivariate meta-analysis / Ovčariček, Petra Petranović (Rights reserved)
A robust ddPCR assay for the absolute quantification of miR-192-5p in hepatocellular carcinoma liquid biopsies / Liu, Xinmiao (Rights reserved)
Thresholds adjustments and impact on clinical performance of three FIT assays in a colorectal cancer screening program / Dubé, Jean (Rights reserved)
Hemolysis index. Can we uncritically trust manufacturer declarations? / Vrtaric, Alen (Rights reserved)
VeRUS: verification of reference intervals based on the uncertainty of sampling / Beck, Matthias (CC BY)
ReferenceRangeR: a novel tool designed to facilitate reference interval estimation and verification / Brandhorst, Gunnar (Rights reserved)
Use of indirect methods and machine learning algorithms for the estimation of reference intervals, taking cortisol measurements as an example / Arslan, Fatma Demet (Rights reserved)
Spot urine is a suitable matrix for measurement of copeptin / Sherfan, Julie (Rights reserved)
Towards a global framework of entrustable professional activities for undergraduate clinical laboratory interns: a competency-based approach / Zhang, Xiaohui (CC BY)
Creatinine measurement from finger stick dried blood spots with a routine chemistry analyzer for estimation of GFR / van Dam, J. Corné (CC BY)
Short- and medium-term pre-analytical stability of human serum insulin-like growth factor-1 / Louw, Jaco C. (CC BY)
Development and validation of a machine learning model for accurate detection of wrong blood in tube errors in hospitalized patients / Tortosa-Carreres, Jordi (Rights reserved)
Optimization and comparison of genomic DNA extraction from whole blood collected in PAXgene blood RNA tube using automated platforms / You, Jianlan (CC BY)
Small-scale external quality assessment of methylated SHOX2 and RASSF1A detection in China: findings from 2023–2024 / Chu, Chengxiang (Rights reserved)
Recommendations for the study of monoclonal gammopathies in the clinical laboratory. A consensus of the Spanish Society of Laboratory Medicine and the Spanish Society of Hematology and Hemotherapy. Part III: Clinical and analytical recommendations for the study of monoclonal gammopathies by MALDI-TOF mass spectrometry / Agulló, Cristina (CC BY)
Strategy of Laboratory Medicine – EFLM Vision / Plebani, Mario (Rights reserved)
Point of care testing of biochemical markers for monitoring astronauts during long duration missions in deep space / Ferraro, Simona (Rights reserved)
Methodological evaluation and clinical interpretation of hs-cTnI and hs-cTnT variations: a reappraisal / Clerico, Aldo (Rights reserved)
Secondary use of external quality assessment data – estimating inter-assay variation in LOINC-coded datasets / Vogeser, Michael (CC BY)
Supporting trend detection in the cumulative display of electronic laboratory reports from multiple laboratories while preserving measurement provenance / Bietenbeck, Andreas Christoph Niklas (Rights reserved)
Mass spectrometry based precision diagnostics: on the cusp of selective testing / van der Helm, Michelle P. (CC BY)
The European Health Data Space: challenges and opportunities for laboratory medicine / Vermeersch, Pieter (Rights reserved)
Saliva sampling matters for salivary diagnostics of viral infections / Kong, Chuixi (Rights reserved)
ROTEM-guided diagnostic pathway in a centralized Laboratory Medicine setting: an organizational report / Bovara, Monica (Rights reserved)
Familial erythrocytosis and phenotypic heterogeneity associated with different defects in alpha globin genes: a significant new case of Hb Wroclaw (α88 (F9) Ala>Glu; HBA1: c.266C>A) / Carrai, Valentina (Rights reserved)
Potential savings of two practical interventions on vitamin D ordering practices at a large academic medical center / Hart, Stephanie A. (CC BY)
Interference with immunofixation in a dabigatran-overdosed patient treated with idarucizumab: beware of a diagnostic pitfall / Pomorski, Quentin (Rights reserved)
Cross reactivity of endogenous and exogenous 25-hydroxyvitamin D 2 in commercial vitamin D assays; an evaluation using the Dutch external quality assessment scheme / Huijser, Erika (CC BY)
Pitfalls of immunoassays for diagnosis of hypoglycemia of undetermined etiology / Ismail, Adel A.A. (Rights reserved)
Biological variation of serum transthyretin concentrations / Stefanska, Anna (Rights reserved)
Frontmatter (Rights reserved)
Comparison of the cardiac troponin I-cardiac troponin T-troponin C complex and cardiac troponin I and T in distinguishing myocardial infarction using a single sample at presentation / Li, Ling (Rights reserved)
Flow cytometry, cytology and histology in the diagnosis of ocular hematologic neoplasms: a 15-year monocentric experience with a focus on ocular lymphomas / Falda, Alessandra (Rights reserved)
EQALM recommendations for the analytical performance specifications for blood smear interpretation in hematology: a need for standardization / Albarède, Stéphanie (Rights reserved)
Performance evaluation of quantitative hemoglobin A 2 and fetal hemoglobin testing using commercially lyophilized vs. in-house whole blood controls in Chinese clinical laboratories: a 12-year analysis of National External Quality Assessment Data / Ma, Yating (Rights reserved)
Serum neuron-specific enolase – reference interval in Danish children and the impact of preanalytical factors / Therkildsen, Jacob Rudjord (Rights reserved)
Establishing reference intervals for high-sensitivity cardiac troponin T in neonates and infants / Li, Yue-Qi (Rights reserved)
Dental amalgams and blood mercury concentrations in American adults / Geier, David A. (CC BY)
Influence of remnant cholesterol on direct LDL and HDL cholesterol measurement accuracy / Kwon, Soon Sung (CC BY)
ADORE: the performance characteristics of five automated platforms in the analysis of urinary dysmorphic erythrocytes and pathological casts / Luimstra, Jolien J. (Rights reserved)
Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays / Sheth, Udit (Rights reserved)
Staining and serological characteristics of the AC-30 pattern in HEp-2 IIFA: a comparative study with AC-2 pattern / Deng, Chuiwen (Rights reserved)
Towards harmonization of autoantibody detection in relation to paraneoplastic neurological syndromes (PNS): a European Survey on laboratory practices / Oyaert, Matthijs (Rights reserved)
Post-analytical practices in clinical mass spectrometry laboratories: an international survey across 57 countries / Cheng, Jenny Yeuk-ki (Rights reserved)
Estimated waste generation from 1 million basic metabolic panels: a multisite U.S. study / Khattri Bhandari, Seema (CC BY)
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients / Puravet, Antoine (Rights reserved)
Comparative analysis of ISO 15189:2022 with earlier versions with reference to ethics / Datta, Sudip K. (Rights reserved)
Requiem for the Passing–Bablok nonparametric regression in assessing the agreement between two measurement methods / Cesana, Bruno Mario (Rights reserved)
Impact of pneumatic tube system transport and blood collection tubes on cell-free DNA analysis of plasma samples / do Canto, Luisa Matos (CC BY)
Failure Mode and Effects Analysis (FMEA) integrating quality indicators for risk assessment of the total testing process in human papillomavirus genotyping testing: a proactive risk analysis model for molecular diagnostics / Li, Tingting (Rights reserved)
Does patient-based data monitoring allow us to reconsider the relationship between IQC and EQA? / Badrick, Tony (Rights reserved)
Predictive genomic medicine enlarges the spectrum of predisposing mutations for head and neck cancers via a panel of 56 genes selected for human neoplasia in Southern Italy: a pilot study / Di Maggio, Federica (CC BY)
Expert opinion within the context of the targeted evaluation of Regulation (EU) 2017/746 on in vitro diagnostic medical devices pursuant to Article 111 and Regulation (EU) 2024/1860 / Vogeser, Michael (Rights reserved)
Value is equal to outcome/costs: how to apply to laboratory medicine / Tomaiuolo, Rossella (Rights reserved)
Automated reticulocyte counting: advances, standardization challenges, and clinical accessibility / Zhou, Hongyin (CC BY)
Multi-cancer early detection revisited: insights and lessons from the PATHFINDER 2 study / Lippi, Giuseppe (Rights reserved)
Counting cells is not enough: toward a global vision for quality and training in hematology / Pelloso, Michela (CC BY)
Ionized calcium in serum exposed to air / Mirdell, Robin (CC BY)
Adverse analytical finding with trimetazidine after ingesting contaminated melatonin tablets sold in pharmacies… leading to the suspension of the athlete / Alvarez, Jean-Claude (Rights reserved)
Confirmation of the value of the labile HbA 1c/HbA 1c -ratio in the presence of a Hb J-Baltimore variant: a clinical case / Lenters-Westra, Erna (Rights reserved)
Early autoimmune signature in a young woman: palmar erythema, capillaroscopic abnormalities, and triple autoantibody positivity including anti-nucleosome / Nigro, Angelo (Rights reserved)
Pleural effusion with a thyroid signature: diagnostic utility of pleural fluid thyroglobulin / Giovanella, Luca (Rights reserved)
Annual meeting of the Royal Belgian Society of Laboratory Medicine (RBSLM): “Beyond the Surface – Clinical biology of the apparently healthy individual” (Rights reserved)
Beyond cut-offs: optimizing presepsin for neonatal late-onset sepsis / Auriti, Cinzia (Rights reserved)
Critical appraisal of presepsin for diagnosing late-onset sepsis in critically ill neonates / Wang, XiaoMei (Rights reserved)
Frontmatter (Rights reserved)
Reviewer Acknowledgment (Rights reserved)
Proadrenomedullin for prediction of early and mid-term mortality in patients hospitalized for community-acquired pneumonia / Artaraz, Amaia (Rights reserved)
Comparative analysis of monocyte distribution width alterations in Escherichia coli sepsis: insights from in vivo and ex vivo models / Ligi, Daniela (CC BY)
Comparison of seven different enzymatic methods for serum glycated albumin in pregnant women: a multicenter study / Sun, Dandan (Rights reserved)
Analysis of total cholesterol results measured in the initial period of the Croatian screening program for familial hypercholesterolemia: a pilot study / Juričić, Gordana (Rights reserved)
An automatic chemiluminescence immunoassay for a novel biomarker NT-IGFBP-4: analytical performance and clinical relevance in heart failure / Cao, Shuzheng (Rights reserved)
Defining the analytical characteristics of a novel high-sensitivity point-of-care troponin I assay in its intended clinical environment / Hatherley, James (Rights reserved)
CA-125 glycovariant assays enhance diagnostic sensitivity in the detection of epithelial ovarian cancer / Moukas, Stefanos (CC BY)
Fecal leukocyte esterase levels predict endoscopic severity as an alternative biomarker in inflammatory bowel disease / Tsai, Feng-Pai (Rights reserved)
Impact of renal and hepatic function on dihydropyrimidine dehydrogenase phenotype assessed by enzyme activity in peripheral blood mononuclear cells and uracilemia / Contu, Sara (Rights reserved)
Age distorts the interpretation of FIB-4 / Åsberg, Arne (CC BY)
Not all anti-parietal cell antibody tests are equal for diagnosing pernicious anemia / Lacombe, Valentin (Rights reserved)
Quality assurance using patient split samples: recommendations for primary healthcare laboratories / Stavelin, Anne (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry based candidate reference measurement procedure for the simultaneous quantification of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum and plasma / Kandler, Kerstin (CC BY)
Isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedures for the quantification of total and free phenytoin in human serum and plasma / Schierscher, Tobias (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 17β-estradiol in human serum and plasma / Ott, Myriam (CC BY)
Candidate reference measurement procedure based on isotope dilution-two dimensional-liquid chromatography-tandem mass spectrometry for the quantification of androstenedione in human serum and plasma / Ott, Myriam (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisone in human serum and plasma / Ott, Myriam (CC BY)
Isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedures for the quantification of 24 (R), 25-dihydroxyvitamin D2 and 24 (R), 25-dihydroxyvitamin D3 in human serum and plasma / Kandler, Kerstin (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisol in human serum and plasma / Ott, Myriam (CC BY)
EFLM checklist for the assessment of AI/ML studies in laboratory medicine: enhancing general medical AI frameworks for laboratory-specific applications / Carobene, Anna (Rights reserved)
Total laboratory automation: fit for its intended purposes? / Plebani, Mario (CC BY)
Toxic beauty: acute kidney injury triggered by hair-straightening treatment / Pons-Belda, Oscar D. (Rights reserved)
Rethinking the use of “one-way ANOVA” in CLSI EP15-A3 – a call for terminological precision and methodological clarity / Ma, Chaochao (Rights reserved)
Improvement in the turnaround time of PTH (1–84) as part of the intraoperative PTH monitoring for parathyroidectomy / Buffart, Beverly (Rights reserved)
Tafasitamab interference in immunofixation electrophoresis / Treger, Rebecca S. (CC BY)
Are vitamins A and E results truly traceable and clinically useful? A practical and critical inquiry / Rigo-Bonnin, Raúl (Rights reserved)
The role of AI in pre-analytical phase – use cases / Çubukçu, Hikmet Can (Rights reserved)
Frontmatter (Rights reserved)
Keeping pace with patient safety by developing and qualifying higher-order reference measurement procedures for laboratory measurement standardization / Panteghini, Mauro (Rights reserved)
57 th National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC – Laboratory Medicine) (Rights reserved)
Biological variation of serum Golgi protein 73 concentrations / Stefanska, Anna (Rights reserved)
Multivariate approaches to improve the interpretation of laboratory data / Plebani, Mario (CC BY)
Method comparison of plasma and CSF GFAP immunoassays across multiple platforms / Arslan, Burak (CC BY)
HCV serology: an unfinished agenda / Galli, Claudio (Rights reserved)
Verification of the T50 Calciprotein Crystallization test: bias estimation and interferences / Xu, Joyce Y. (CC BY)
A multiplex allele specific PCR capillary electrophoresis (mASPCR-CE) assay for simultaneously analysis of SMN1/SMN2/NAIP copy number and SMN1 loss-of-function variants / Lai, Yunli (Rights reserved)
Assessing the harmonization of current total vitamin B12 measurement methods: relevance and implications / Cesana, Bruno Mario (Rights reserved)
Supplementation of pyridoxal-5′-phosphate in aminotransferase reagents: a matter of patient safety / Panteghini, Mauro (Rights reserved)
Comparative analysis of population-based and personalized reference intervals for biochemical markers in peri-menopausal women: population from the PALM cohort study / Wu, Jiaming (Rights reserved)
Urgent call to the European Commission to simplify and contextualize IVDR Article 5.5 for tailored and precision diagnostics / Cobbaert, Christa (CC BY)
Clinical significance of anti-mitochondrial antibodies and PBC-specific anti-nuclear antibodies in evaluating atypical primary biliary cholangitis with normal alkaline phosphatase levels / Li, Shasha (CC BY)
Analytical and clinical evaluation of an automated high-sensitivity cardiac troponin I assay for whole blood / Yu, Jin-xing (Rights reserved)
Method comparison of diabetes mellitus associated autoantibodies in serum specimens / Lenard, Alexander (CC BY)
From metabolic profiles to clinical interpretation: multivariate approaches to population-based and personalized reference intervals and reference change values / Coskun, Abdurrahman (Rights reserved)
Establishment of region-, age- and sex-specific reference intervals for aldosterone and renin with sandwich chemiluminescence immunoassays / Cao, Lin-Lin (Rights reserved)
Interference of therapeutic monoclonal antibodies with electrophoresis and immunofixation of serum proteins: state of knowledge and systematic review / Pelletier, Sacha (CC BY)
Validation of a plasma GFAP immunoassay and establishment of age-related reference values: bridging analytical performance and routine implementation / Arslan, Burak (CC BY)
Oral salt loading combined with postural stimulation tests for confirming and subtyping primary aldosteronism / Cheng, Jenny Yeuk Ki (CC BY)
Evaluation of measurement uncertainty of 11 serum proteins measured by immunoturbidimetric methods according to ISO/TS 20914: a 1-year laboratory data analysis / Yurt, Emine Feyza (Rights reserved)
Challenging the dogma: why reviewers should be allowed to use AI tools / Lippi, Giuseppe (Rights reserved)
Cerebrospinal fluid leptin in Alzheimer’s disease: relationship to plasma levels and to cerebrospinal amyloid / Bouaziz-Amar, Elodie (Rights reserved)
From assessment to action: experience from a quality improvement initiative integrating indicator evaluation and adverse event analysis in a clinical laboratory / Chen, Peirong (Rights reserved)
An innovative immunoassay for accurate aldosterone quantification: overcoming low-level inaccuracy and renal dysfunction-associated interference / Wang, Kaijuan (Rights reserved)
The current status of serum insulin measurements and the need for standardization / Rohlfing, Curt (Rights reserved)
The importance of laboratory medicine in the management of CKD-MBD: insights from the KDIGO 2023 controversies conference / Vasikaran, Samuel D. (Rights reserved)
Evaluating the performance of a multiparametric IgA assay for celiac disease diagnosis / Gambino, Caterina Maria (Rights reserved)
Evaluation of stability and potential interference on the α-thalassaemia early eluting peak and immunochromatographic strip test for α-thalassaemia -- SEA carrier screening / Lam, Wing Kit (Rights reserved)
16th Congress of the Portuguese Society of Clinical Chemistry, Genetics and Laboratory Medicine (Rights reserved)
Association of Clinical Biochemists in Ireland Annual Conference (Rights reserved)
Association of Clinical Biochemists in Ireland Annual Conference (Rights reserved)
Kidney stones consisting of 1-methyluric acid / Kristensen, Søren Risom (Rights reserved)
Response to the editorial by Karl Lackner / van Schrojenstein Lantman, Marith (CC BY)
Recent decline in patient serum folate test levels using Roche Diagnostics Folate III assay / Larsson, Anders (CC BY)
Hemolysis detection using the GEM 7000 at the point of care in a pediatric hospital setting: does it affect outcomes? / Ibrahim, Ridwan B. (CC BY)
Permitting disclosed AI assistance in peer review: parity, confidentiality, and recognition / Carobene, Anna (Rights reserved)
Accelerating time from result to clinical action: impact of an automated critical results reporting system / Aponte, Elisa M. (Rights reserved)
Estimation of measurement uncertainty for free drug concentrations using ultrafiltration / Rigo-Bonnin, Raúl (Rights reserved)
Cryoglobulin pre-analysis over the weekend / de Kat Angelino, Corrie (CC BY)
Frontmatter (Rights reserved)
7th EFLM Conference on Preanalytical Phase (Rights reserved)
IFCC recommendations for internal quality control practice: a missed opportunity / Çubukçu, Hikmet Can (Rights reserved)
New insights in preanalytical quality / Plebani, Mario (Rights reserved)
Improving the efficiency of quality control in clinical laboratory with an integrated PBRTQC system based on patient risk / Duan, Xincen (Rights reserved)
Analytical validation of hemolysis detection on GEM Premier 7000 / Pighi, Laura (CC BY)
Reconciling reference ranges and clinical decision limits: the case of thyroid stimulating hormone / Giovanella, Luca (Rights reserved)
Vitamin D metabolome in preterm infants: insights into postnatal metabolism / Matejek, Tomas (Rights reserved)
Screening primary aldosteronism by plasma aldosterone-to-angiotensin II ratio / Lo, Clara Wai-Shan (CC BY)
IgA-type macroprolactin among 130 patients with macroprolactinemia / Ishihara, Masayuki (Rights reserved)
The Unholy Grail of cancer screening: or is it just about the Benjamins? / Chatanaka, Miyo K. (Rights reserved)
Beyond the Hydrashift assay: the utility of isoelectric focusing for therapeutic antibody and paraprotein detection / Reiter, Rieke (Rights reserved)
Effect of long-term frozen storage on stability of kappa free light chain index / Schmidauer, Martin (CC BY)
Defining dried blood spot diameter: implications for measurement and specimen rejection rates / Flynn, Nick (Rights reserved)
Macroprolactinaemia – some progress but still an ongoing problem / Fahie-Wilson, Michael N. (Rights reserved)
Pre-analytical phase errors constitute the vast majority of errors in clinical laboratory testing / Lin, Yanchun (Rights reserved)
Evaluation of error detection and treatment recommendations in nucleic acid test reports using ChatGPT models / Han, Wenzheng (Rights reserved)
Direct screening and quantification of monoclonal immunoglobulins in serum using MALDI-TOF mass spectrometry without antibody enrichment / Luo, Hou-Long (Rights reserved)
Diagnostic performance of morphological analysis and red blood cell parameter-based algorithms in the routine laboratory screening of heterozygous haemoglobinopathies / Simon, Germain (Rights reserved)
Prevalence and re-evaluation of macroprolactinemia in hyperprolactinemic patients: a retrospective study in the Turkish population / Oğuz, Osman (Rights reserved)
The accuracy of presepsin in diagnosing neonatal late-onset sepsis in critically ill neonates: a prospective study / Auriti, Cinzia (Rights reserved)
Assessment of serum free light chain measurements in a large Chinese chronic kidney disease cohort: a multicenter real-world study / Luo, Xia (Rights reserved)
Potential coeliac disease in children: a single-center experience / Lonoce, Luisa (Rights reserved)
Development of commutable candidate certified reference materials from protein solutions: concept and application to human insulin / Luo, Shiwen (Rights reserved)
Biological variation of serum cholinesterase activity in healthy subjects / Akbulut, Emiş Deniz (Rights reserved)
Frontmatter (Rights reserved)
Standardization challenges in antipsychotic drug monitoring: insights from a national survey in Chinese TDM practices / Zhou, Weiyan (Rights reserved)
Promising protein biomarkers for early gastric cancer: clinical performance of combined detection / Shen, Weifeng (Rights reserved)
Understanding the circulating forms of cardiac troponin: insights for clinical practice / Lv, Panpan (Rights reserved)
Impact of renal function impairment on kappa free light chain index / Schmidauer, Martin (CC BY)
Contradictory definitions give rise to demands for a right to unambiguous definitions / Buchta, Christoph (Rights reserved)
Biomarkers to measure the need and the effectiveness of therapeutic supplementation: a critical issue / Ferraro, Simona (Rights reserved)
A novel immunoprecipitation-based targeted liquid chromatography-tandem mass spectrometry analysis for accurate determination for copeptin in human serum / Mu, Danni (Rights reserved)
Regulating the future of laboratory medicine: European regulatory landscape of AI-driven medical device software in laboratory medicine / Çubukçu, Hikmet Can (Rights reserved)
Australasian guideline for the performance of sweat chloride testing 3rd edition: to support cystic fibrosis screening, diagnosis and monitoring / Massie, John (CC BY)
A comparison of current methods to measure antibodies in type 1 diabetes / Infantino, Maria (Rights reserved)
Health-related reference intervals for heavy metals in non-exposed young adults / Di Resta, Chiara (Rights reserved)
Comprehensive assessment of medical laboratory performance: a 4D model of quality, economics, velocity, and productivity indicators / Zubanov, Pavel S. (Rights reserved)
A single dose of 20-mg of ostarine is detectable in hair / Alvarez, Jean-Claude (Rights reserved)
Practical handling of hemolytic, icteric and lipemic samples for coagulation testing in European laboratories. A collaborative survey from the European Organisation for External Quality Assurance Providers in Laboratory Medicine (EQALM) / Kristoffersen, Ann Helen (CC BY)
False-positive cardiac troponin I values due to macrotroponin in healthy athletes after COVID-19 / Hammerer-Lercher, Angelika (CC BY)
Histamine metabolite to basal serum tryptase ratios in systemic mastocytosis and hereditary alpha tryptasemia using a validated LC-MS/MS approach / Alheraky, Abdulrazzaq (CC BY)
Detecting cardiac injury: the next generation of high-sensitivity cardiac troponins improving diagnostic outcomes / Lippi, Giuseppe (Rights reserved)
A cost-effective assessment for the combination of indirect immunofluorescence and solid-phase assay in ANA-screening / Gallo, Nicoletta (CC BY)
Quality indicators: an evolving target for laboratory medicine / Plebani, Mario (CC BY)
62nd National Congress of the Hungarian Society of Laboratory Medicine Szeged, Hungary, August 28–30, 2025 (CC BY)
Machine learning algorithms with body fluid parameters: an interpretable framework for malignant cell screening in cerebrospinal fluid / Ye, Xianfei (Rights reserved)
Commutability evaluation of glycated albumin candidate EQA materials / Wu, Rui (Rights reserved)
Impact of analytical bias on machine learning models for sepsis prediction using laboratory data / Yesil, Meryem Rumeysa (Rights reserved)
The spectrum of nuclear patterns with stained metaphase chromosome plate: morphology nuances, immunological associations, and clinical relevance / de Melo Cruvinel, Wilson (Rights reserved)
High myoglobin plasma samples risk being reported as falsely low due to antigen excess – follow up after a 2-year period of using a mitigating procedure / Olsson, Anders O. (CC BY)
Growing importance of vocabularies in medical laboratories / Pradella, Marco (Rights reserved)
Error in prostate-specific antigen levels after prostate cancer treatment with radical prostatectomy / Martens, Remy J.H. (Rights reserved)
Arivale is dead ‒ Hooke is alive / Chatanaka, Miyo K. (Rights reserved)
Frontmatter (Rights reserved)
Assessment of measurement uncertainty of immunoassays and LC-MS/MS methods for serum 25-hydroxyvitamin D / Cavalier, Etienne (Rights reserved)
Serum biomarkers as early indicators of outcomes in spontaneous subarachnoid hemorrhage / Auricchio, Anna Maria (Rights reserved)
The neglected issue of pyridoxal- 5′ phosphate / Ricós, Carmen (Rights reserved)
Recommendations for the integration of standardized quality indicators for glucose point-of-care testing / Shaw, Julie L.V. (CC BY)
Immunochemical measurement of urinary free light chains and Bence Jones proteinuria / Michetti, Laura (Rights reserved)
Assessment of atypical cells in detecting bladder cancer in female patients / Zhao, Yan (Rights reserved)
Can Theranos resurrect from its ashes? / Chatanaka, Miyo K. (Rights reserved)
Flow-cytometric lymphocyte subsets enumeration: comparison of single/dual-platform method in clinical laboratory with dual-platform extended PanLeucogating method in reference laboratory / Hu, Gaofeng (Rights reserved)
Use of the BIOGROUP ® French laboratories database to conduct CKD observational studies: a pilot EPI-CKD1 study / Visseaux, Claire (Rights reserved)
External quality assessment in resource-constrained laboratories: a survey of practices and perceptions in Nepal / Pant, Vivek (Rights reserved)
Acoustophoresis-based blood sampling and plasma separation for potentially minimizing sampling-related blood loss / Nath, Amal (CC BY)
Oligoclonal banding analysis: assessing plasma use and time interval requirements for paired CSF and blood / Olayinka, Lily (Rights reserved)
Is successfulness of platelet clump disaggregation by vortexing influenced by platelet measurement methods? / Radišić Biljak, Vanja (Rights reserved)
Frontmatter (Rights reserved)
Overview of laboratory diagnostics for immediate management of patients presenting to the emergency department with acute bleeding / Lippi, Giuseppe (Rights reserved)
Utilization analysis of laboratory tests using health insurance claims data: advancing nationwide diagnostic stewardship monitoring systems / Koo, Se-eun (Rights reserved)
Biomarkers in body fluids and their detection techniques for human intestinal permeability assessment / Zhang, Jian (Rights reserved)
Reference intervals in value-based laboratory medicine: a shift from single-point measurements to metabolic variation-based models / Coskun, Abdurrahman (Rights reserved)
Advancing diagnostic stewardship through claims-based utilization analysis: toward a system-wide vision of diagnostic excellence / Rubinstein, Matthew L. (CC BY)
Clinical validation of a liquid chromatography single quadrupole mass spectrometry (LC-MS) method using Waters Kairos™ Amino Acid Kit reagents / Hellier, Rowan (Rights reserved)
An assessment of molecular diagnosis of tuberculosis and multi-drug resistant tuberculosis testing and quality assessment: findings of an international survey / Huggett, Jim (CC BY)

An assessment of molecular diagnosis of tuberculosis and multi-drug resistant tuberculosis testing and quality assessment: findings of an international survey / Huggett, Jim (CC BY)
Robustness of steroidomics-based machine learning for diagnosis of primary aldosteronism: a laboratory medicine perspective / Eisenhofer, Graeme (Rights reserved)
Exploring commutable materials for serum folate measurement: challenges in cross-method harmonization / Nizhamuding, Xiaerbanu (Rights reserved)
Serum N-glycans as independent predictors of the incidence of type 2 diabetes: a prospective investigation in the AEGIS cohort / Carballo, Iago (Rights reserved)
Cellular expression of PD-1, PD-L1 and CTLA-4 in patients with JAK2 V617F mutated myeloproliferative disorders / Winkler, Christoph (Rights reserved)
Assessment of 2023 ACR/EULAR antiphospholipid syndrome classification criteria in a Spanish cohort / Cantera Estefanía, Rodrigo (Rights reserved)
Performance of afternoon (16:00 h) serum cortisol for the diagnosis of Cushing’s syndrome / Dupuis, Hippolyte (Rights reserved)
A novel corrective model based on red blood cells indices and haemolysis index enables accurate unhaemolysed potassium determination in haemolysed samples – Hemokalc project / Lefèvre, Charles R. (Rights reserved)
No fault or negligence after an adverse analytical finding due to a contaminated supplement: mission impossible. Two examples involving trimetazidine / Kintz, Pascal (Rights reserved)
Is time a significant factor in the release of potassium from lithium heparin plasma and serum? / Petersmann, Astrid (Rights reserved)
Targeting low-value laboratory care / Vogeser, Michael (Rights reserved)
Comprehensive evaluation of antiphospholipid antibody testing methodologies in APS diagnosis: performance comparisons across assay systems and clinical subtypes / Wang, Yun (Rights reserved)
Validation of (self-collected) capillary blood using a topper collection system as alternative for venous sampling for 15 common clinical chemistry analytes / Geujar, Rümeysa (Rights reserved)
Challenges of using natriuretic peptides to screen for the risk of developing heart failure in patients with diabetes: a report from the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) / Jaffe, Allan S. (Rights reserved)
Investigation of the possible cause of over-estimation of human aldosterone in plasma, using a unique, non-synthetic human aldosterone-free matrix / Stoner, Sheree (Rights reserved)
Reference ranges for ionized calcium in plasma in Danish children aged 0 days to 3 years using laboratory registry data / Faarvang, Anne-Sofie Allermann (Rights reserved)
MAGLUMI ® Tacrolimus (CLIA) assay: analytical performances and comparison with LC-MS/MS and ARCHITECT Tacrolimus (CMIA) assay / Fu, Mingpeng (Rights reserved)
A step forward in pediatric hemophagocytic lymphohistiocytosis and autoimmune disease: pediatric reference interval for serum soluble IL-2 receptor and soluble CD163 / Bruun, Victor (Rights reserved)
Evaluating large language models as clinical laboratory test recommenders in primary and emergency care: a crucial step in clinical decision making / Zayed, Ahmed Medhat (CC BY)
What Matters Most: an Age-Friendly approach to pathology and laboratory medicine / Nelson, Melody Boudreaux (Rights reserved)
Impact of high-sensitivity cardiac troponin I assay imprecision on the safety of a single-sample rule-out approach for myocardial infarction / Li, Ziwen (CC BY)
Utility and limitations of monitoring kidney transplants using capillary sampling / Whitbread, Daniel J. (Rights reserved)
Lab Error Finder: A call for collaboration / Çubukçu, Hikmet Can (Rights reserved)
SYMPOSIUM 4 - Defining analytical performance requirements for laboratory tests to make them fit for clinical purpose (Rights reserved)
SYMPOSIUM 10 - How can we integrate proteomics and metabolomics in Clinical Lab? (Rights reserved)
Healthcare reform: from curative to preventive (Rights reserved)
Assessment of cardiovascular risk and physical activity: the role of cardiac-specific biomarkers in the general population and athletes / Clerico, Aldo (Rights reserved)
Ethical Checklists for Clinical Research Projects and Laboratory Medicine: two tools to evaluate compliance with bioethical principles in different settings / Verona, Julián (Rights reserved)
Tumor markers determination in malignant pleural effusion: pearls and pitfalls / Zheng, Wen-Qi (Rights reserved)
A promising new direct immunoassay for urinary free cortisol determination / Raverot, Véronique (CC BY)
Does blood tube filling influence the Athlete Biological Passport variables? / Krumm, Bastien (Rights reserved)
IFCC SYMPOSIUM 2 - Future laboratory IT systems and standardized laboratory terminology (Rights reserved)
The first case of Teclistamab interference with serum electrophoresis and immunofixation / Kadkhoda, Kamran (Rights reserved)
Navigating complexities in vitamin D and cardiovascular health: a call for comprehensive analysis / Xie, Shanzhen (Rights reserved)
PLENARY LECTURE 1 - Clinical proteomics: More precision in precision oncology - adding phosphoproteomics to the molecular tumor board (Rights reserved)
Committees (Rights reserved)
Frontmatter (Rights reserved)
Behind the scenes of EQA–characteristics, capabilities, benefits and assets of external quality assessment (EQA) / Buchta, Christoph (Rights reserved)
Vitamin B12 deficiency in newborns: impact on individual’s health status and healthcare costs / Ferraro, Simona (Rights reserved)
The surveys on quality indicators for the total testing process in clinical laboratories of Fujian Province in China from 2018 to 2023 / Li, Yao (Rights reserved)
Assessing the clinical applicability of dimensionality reduction algorithms in flow cytometry for hematologic malignancies / Park, Min-Seung (CC BY)
Comparative analysis of BCR::ABL1 p210 mRNA transcript quantification and ratio to ABL1 control gene converted to the International Scale by chip digital PCR and droplet digital PCR for monitoring patients with chronic myeloid leukemia / Saisaard, Wannachai (CC BY)
Regulations and Regulatory Science, including suboptimal tests and post-market follow-up (Rights reserved)
Hematology and hemostasis (Rights reserved)
An improved implementation of metrological traceability concepts is needed to benefit from standardization of laboratory results / Panteghini, Mauro (Rights reserved)
Why is single sample rule out of non-ST elevation myocardial infarction using high-sensitivity cardiac troponin T safe when analytical imprecision is so high? A joint statistical and clinical demonstration / Hatherley, James Daniel (Rights reserved)
Particulate matter in water: an overlooked source of preanalytical error producing erroneous chemistry test results / Wang, Tong (Rights reserved)
An appeal for biological variation estimates in deep immunophenotyping / Guo, Kai (Rights reserved)
SYMPOSIUM 3 - AntiMicrobial Stewardship in real praxis (Rights reserved)
Clinical Chemistry (Rights reserved)
Interference of hypertriglyceridemia on total cholesterol assay with the new CHOL2 Abbott method on Architect analyser / Terrasse, Mélina (Rights reserved)
Sigma Metrics misconceptions and limitations / Duan, Xincen (Rights reserved)
RBSLM SYMPOSIUM 1 - Improving quality in the extra-analytical phase (Rights reserved)
Laboratory Information Systems and globalization of NPU (Rights reserved)
Remote monitoring and preanalytical challenges (Rights reserved)
Novel Mindray high sensitivity cardiac troponin I assay for single sample and 0/2-hour rule out of myocardial infarction: MERITnI study / Buda, Kevin G. (Rights reserved)
Performance evaluation of large language models with chain-of-thought reasoning ability in clinical laboratory case interpretation / Yang, He S. (Rights reserved)
Recruitment, Education and Training of workforces in Laboratory Medicine (Rights reserved)
Frontmatter (Rights reserved)
A comprehensive survey of artificial intelligence adoption in European laboratory medicine: current utilization and prospects / Cadamuro, Janne (Rights reserved)
EN ISO 15189 revision: EFLM Committee Accreditation and ISO/CEN standards (C: A/ISO) analysis and general remarks on the changes / Linko, Solveig (Rights reserved)
Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine / Dong, Xingli (Rights reserved)
Early rule-out high-sensitivity troponin protocols require continuous analytical robustness: a caution regarding the potential for troponin assay down-calibration / Trambas, Christina M. (Rights reserved)
IFCC SYMPOSIUM 4 - Cardiac troponins; clinical utility, analytical performance and future opportunities (Rights reserved)
SYMPOSIUM 6 - Environmental Impact of Laboratory Medicine (Green and Sustainable Medical Laboratories) (Rights reserved)
Endocrinology (Rights reserved)
New concept for control material in glucose point-of-care-testing for external quality assessment schemes / Kaiser, Patricia (CC BY)
The role of functional vitamin D deficiency and low vitamin D reservoirs in relation to cardiovascular health and mortality / Herrmann, Markus (CC BY)
Hb D-Iran interference on HbA 1c measurement / Iacomelli, Iacopo (Rights reserved)
SYMPOSIUM 12 - AI in the extranalytical phases (Rights reserved)
Laboratory Management, Medical leadership (Rights reserved)
Frontmatter (Rights reserved)
Allowable total error in CD34 cell analysis by flow cytometry based on state of the art using Spanish EQAS data / Fernández-Luis, Sara (Rights reserved)
A comparative analysis of current С-peptide assays compared to a reference method: can we overcome inertia to standardization? / Rohlfing, Curt (Rights reserved)
Clostebol detection after transdermal and transmucosal contact. A systematic review / Menditto, Vincenzo Giannicola (Rights reserved)
Development and validation of a novel 7α-hydroxy-4-cholesten-3-one (C4) liquid chromatography tandem mass spectrometry method and its utility to assess pre-analytical stability / Atkins, Jonathan S. (Rights reserved)
Adult reference intervals for serum thyroid‐stimulating hormone using Abbott Alinity i measuring system / Stefanska, Anna (Rights reserved)
Concentrations and agreement over 10 years with different assay versions and analyzers for troponin T and N-terminal pro-B-type natriuretic peptide / Kavsak, Peter A. (CC BY)
16ª Reunião Científica da Sociedade Portuguesa de Medicina Laboratorial - SPML (Rights reserved)
Contents (Rights reserved)
IVDCheckR – simplifying documentation for laboratory developed tests according to IVDR requirements by introducing a new digital tool / Kaur, Yadwinder (Rights reserved)
Evaluation of biochemical algorithms to screen dysbetalipoproteinemia in ε2ε2 and rare APOE variants carriers / Michenaud, Louise (Rights reserved)
Comment on Lippi et al.: EFLM Task Force Preparation of Labs for Emergencies (TF-PLE) recommendations for reinforcing cyber-security and managing cyber-attacks in medical laboratories / Lapić, Ivana (Rights reserved)
Cardiovascular disease; risk assessment; lipids; lipoproteins; cardiac markers (Rights reserved)
Pre-analytical stability of haematinics, lactate dehydrogenase and phosphate in whole blood at room temperature up to 24 h, and refrigerated serum stability of lactate dehydrogenase, folate and vitamin B12 up to 72 h using the CRESS checklist / Williams, Robert (Rights reserved)
Research on the development of image-based Deep Learning (DL) model for serum quality recognition / Man, Dongliang (Rights reserved)
Use of labile HbA 1c as a screening tool to minimize clinical misinterpration of HbA 1c / De Muynck, Emilie (Rights reserved)
Prevalence and detection of citrate contamination in clinical laboratory / Lorde, Nathan (Rights reserved)
Microbiology - Infectious diseases including COVID 19 (Rights reserved)
Precision Diagnostics and Precision Medicine (Rights reserved)
Inclusion of pyridoxine dependent epilepsy in expanded newborn screening programs by tandem mass spectrometry: set up of first and second tier tests / Damiano, Roberta (Rights reserved)
Simple flow cytometry method using a myeloma panel that easily reveals clonal proliferation of mature B-cells / Araki, Mika (Rights reserved)
Comparison of capillary finger stick and venous blood sampling for 34 routine chemistry analytes: potential for in hospital and remote blood sampling / Doeleman, Martijn J.H. (CC BY)
Dr. Morley Donald Hollenberg. An extraordinary scientist, teacher and mentor / Oikonomopoulou, Katerina (Rights reserved)
RBSLM SYMPOSIUM 3 - New EFLM approaches to urinalysis and urine bacterial culture (Rights reserved)
Emerging biomarkers (-omics type, …) (Rights reserved)
Immunology (Rights reserved)
Clinical performance of a new lateral flow immunoassay for xylazine detection / Contella, Lindsey (Rights reserved)
Generative artificial intelligence (AI) for reporting the performance of laboratory biomarkers: not ready for prime time / Pighi, Laura (Rights reserved)
Performance evaluation of a smartphone-based home test for fecal calprotection / Michaelis, Simon (Rights reserved)
IFCC SYMPOSIUM 3 - Unraveling the Role of Machine Learning in Clinical Chemistry: Bridging the Gap between Potential and Practicality (Rights reserved)
An ultrasensitive DNA-enhanced amplification method for detecting cfDNA drug-resistant mutations in non-small cell lung cancer with selective FEN-assisted degradation of dominant somatic fragments / Zhang, Junhua (CC BY)
Flow-cytometric MRD detection in pediatric T-ALL: a multicenter AIEOP-BFM consensus-based guided standardized approach / Reiterová, Michaela (CC BY)
Clinical utility of regions of homozygosity (ROH) identified in exome sequencing: when to pursue confirmatory uniparental disomy testing for imprinting disorders? / Huo, Xiaoyan (Rights reserved)
Evaluation of sex-specific 0-h high-sensitivity cardiac troponin T thresholds for the risk stratification of non-ST-segment elevation myocardial infarction / Zhang, Ailun (Rights reserved)
Paediatric reference intervals for haematology parameters analysed on Sysmex XN-9000: a comparison of methods in the framework of indirect sampling / Laugesen, Kristina (Rights reserved)
Total Test process, including preanalytics, analytics and postanalytics (Rights reserved)
Analytical performance specifications for trace elements in biological fluids derived from six countries federated external quality assessment schemes over 10 years / Arnaud, Josiane (Rights reserved)
Construction of platelet count-optical method reflex test rules using Micro-RBC#, Macro-RBC%, “PLT clumps?” flag, and “PLT abnormal histogram” flag on the Mindray BC-6800plus hematology analyzer in clinical practice / Fei, Yang (Rights reserved)
Short-term biological variation of coagulation and fibrinolytic measurands / Hollestelle, Martine J. (CC BY)
Nutrition Trace Elements and Vitamins (Rights reserved)
Frontmatter (Rights reserved)
Analytical evaluation of eight qualitative FIT for haemoglobin products, for professional use in the UK / Piggott, Carolyn (Rights reserved)
Performance of the automated digital cell image analyzer UIMD PBIA in white blood cell classification: a comparative study with sysmex DI-60 / Kim, Hongkyung (CC BY)
High sensitivity cardiac troponin assays, rapid myocardial infarction rule-out algorithms, and assay performance / Lackner, Karl J. (Rights reserved)
Laboratory consolidation, Total lab automation and process design (Rights reserved)
Biological variation of cardiac biomarkers in athletes during an entire sport season / Beumer Prieto, Blanca (Rights reserved)
From errors to excellence: the pre-analytical journey to improved quality in diagnostics. A scoping review / John, George K. (CC BY)
Analytical characteristics and performance of a new hs-cTnI method: a multicenter-study / Fasano, Tommaso (Rights reserved)
RBSLM SYMPOSIUM 2 - From preanalytical to postanalytical phase in hematology/hemostasis laboratories (Rights reserved)
Point-of-care testing: state-of-the art and perspectives / Plebani, Mario (CC BY)
Establishing the TSH reference intervals for healthy adults aged over 70 years: the Australian ASPREE cohort study / Tran, Cammie (Rights reserved)
Clostebol and sport: about controversies involving contamination vs. doping offence / Kintz, Pascal (Rights reserved)
Diagnostic performances and cut-off verification of blood pTau 217 on the Lumipulse platform for amyloid deposition in Alzheimer’s disease / Musso, Giulia (CC BY)
PLENARY LECTURE 3 - Bone Forming Agents: Will they help to close the gap in the treatment of post-menopausal osteoporosis (Rights reserved)
Reliable detection of sex chromosome abnormalities by quantitative fluorescence polymerase chain reaction / Balle, Camilla Mains (Rights reserved)
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA) / Buchta, Christoph (Rights reserved)
Artificial base mismatches-mediated PCR (ABM-PCR) for detecting clinically relevant single-base mutations / Lau, Cia-Hin (Rights reserved)
Simple steps to achieve harmonisation and standardisation of dried blood spot phenylalanine measurements and facilitate consistent management of patients with phenylketonuria / Carling, Rachel S. (CC BY)
The effects of drone transportation on routine laboratory, immunohematology, flow cytometry and molecular analyses / Weekx, Steven (Rights reserved)
Artificial intelligence, clinical decision support and machine learning (Rights reserved)
Direct-to-consumer testing as consumer initiated testing: compromises to the testing process and opportunities for quality improvement / Shih, Patti (Rights reserved)
Comparative evaluation of peptide vs. protein-based calibration for quantification of cardiac troponin I using ID-LC-MS/MS / Asicioglu, Meltem (Rights reserved)
Increased specificity of the “GFAP/UCH-L1” mTBI rule-out test by age dependent cut-offs / Ladang, Aurélie (CC BY)
Establishment of ELISA-comparable moderate and high thresholds for anticardiolipin and anti-β2 glycoprotein I chemiluminescent immunoassays according to the 2023 ACR/EULAR APS classification criteria and evaluation of their diagnostic performance / Žigon, Polona (CC BY)
Disease specific biomarkers: autoimmune, bone, cardiac, cancer, diabetes, neurological, sepsis, traumatic brain injury, … (Rights reserved)
EFLM SYMPOSIUM 2 - Value Based Healthcare in Laboratory Medicine (Rights reserved)
Digital metrology in laboratory medicine: a call for bringing order to chaos to facilitate precision diagnostics / Bosma, Madeleen (CC BY)
Interest of hair tests to discriminate a tail end of a doping regimen from a possible unpredictable source of a prohibited substance in case of challenging an anti-doping rule violation / Kintz, Pascal (Rights reserved)
C-terminal alpha-1-antitrypsin peptides as novel predictor of hospital mortality in critically ill COVID-19 patients / Scherr, Franziska (Rights reserved)
Navigation between EQA and sustainability / Badrick, Tony (Rights reserved)
Annual meeting of the Royal Belgian Society of Laboratory Medicine (RBSLM): “A Neurological Journey: Brain Teasers for Laboratory Medicine” (Rights reserved)
IFCC SYMPOSIUM 5 - What 21st century IFCC leadership should be: history, vision, implementation, and opportunities? (Rights reserved)
Performance evaluation of the introduction of full sample traceability system within the specimen collection process / Foglia, Emanuela (CC BY)
Is it feasible for European laboratories to use SI units in reporting results? / Zaninotto, Martina (Rights reserved)
Applying the likelihood ratio concept in external quality assessment for ANCA / Broeders, Sylvia (Rights reserved)
The Friedewald formula strikes back / Langlois, Michel R. (Rights reserved)
Accreditation, Patient Safety, Risk management, Quality Assurance, Audit (Rights reserved)
Molecular diagnostics, including CTC and ctDNA (Rights reserved)
Green laboratories (Rights reserved)
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA) / Buchta, Christoph (Rights reserved)
Clinical vs. statistical significance: considerations for clinical laboratories / Alp, Hamit Hakan (CC BY)
The correlation of albumin with total protein concentrations in cerebrospinal fluid across three automated analysers – relevance to the diagnosis of subarachnoid haemorrhage in clinical chemistry practice / Clarin, Marcus (CC BY)
Clinical value of smear review of flagged samples analyzed with the Sysmex XN hematology analyzer / Winther-Larsen, Anne (CC BY)
Knowledge among clinical personnel on the impact of hemolysis using blood gas analyzers / Nielsen, Trine Muhs (CC BY)
Frontmatter (Rights reserved)
Multi-cancer early detection: searching for evidence / Lippi, Giuseppe (Rights reserved)
Measurement of 1,25-dihydroxyvitamin D in serum by LC-MS/MS compared to immunoassay reveals inconsistent agreement in paediatric samples / Tang, Jonathan C.Y. (CC BY)
The first case of Teclistamab interference with serum electrophoresis and immunofixation / Kadkhoda, Kamran (Rights reserved)
Computer simulation approaches to evaluate the interaction between analytical performance characteristics and clinical (mis) classification: a complementary tool for setting indirect outcome-based analytical performance specifications / Çubukçu, Hikmet Can (Rights reserved)
Verification of automated review, release and reporting of results with assessment of the risk of harm for patients: the procedure algorithm proposal for clinical laboratories / Miler, Marijana (Rights reserved)
Establishing sex- and age-related reference intervals of serum glial fibrillary acid protein measured by the fully automated lumipulse system / Agnello, Luisa (Rights reserved)
Critical appraisal of the CLSI guideline EP09c “measurement procedure comparison and bias estimation using patient samples” / Cesana, Bruno Mario (Rights reserved)
The Unholy Grail of cancer screening: or is it just about the Benjamins? / Chatanaka, Miyo K. (Rights reserved)
Detection of serum CC16 by a rapid and ultrasensitive magnetic chemiluminescence immunoassay for lung disease diagnosis / Duan, Kaili (Rights reserved)
Time to refresh and integrate the JCTLM database entries for total bilirubin: the way forward / Panteghini, Mauro (Rights reserved)
A survey on measurement and reporting of total testosterone, sex hormone-binding globulin and free testosterone in clinical laboratories in Europe / Narinx, Nick (Rights reserved)
Liquid chromatography tandem mass spectrometry (LC-MS/MS) candidate reference measurement procedure for urine albumin / Shiba, Seiei (Rights reserved)
Cell population data in venous thrombo-embolism and erysipelas: a potential diagnostic tool? / Appelboom, Yael (Rights reserved)
Inconsistency in ferritin reference intervals across laboratories: a major concern for clinical decision making / Kurstjens, Steef (Rights reserved)
Towards routine high-throughput analysis of fecal bile acids: validation of an enzymatic cycling method for the quantification of total bile acids in human stool samples on fully automated clinical chemistry analyzers / Masetto, Angelique (CC BY)
Evaluation of AUTION EYE AI-4510 flow cell morphology analyzer for counting particles in urine / Oyaert, Matthijs (CC BY)
PLENARY LECTURE 2 - Sepsis associated acute kidney injury (Rights reserved)
Demand/test utilization management (Rights reserved)
Contribution of laboratory medicine and emerging technologies to cardiovascular risk reduction via exposome analysis: an opinion of the IFCC Division on Emerging Technologies / Gruson, Damien (Rights reserved)
Quality indicators in laboratory medicine: a 2020–2023 experience in a Chinese province / Zhang, Lichao (Rights reserved)
Absolute quantitation of human serum cystatin C: candidate reference method by 15 N-labeled recombinant protein isotope dilution UPLC-MS/MS / Zhang, Qiaoxuan (Rights reserved)
Influence of data visualisations on laboratorians’ acceptance of method comparison studies / Farrell, Christopher-John L. (Rights reserved)
SYMPOSIUM 7 - Medical test standardization in the era of Metrological Traceability: who is accountable? (Rights reserved)
Reviewer Acknowledgment (Rights reserved)
Frontmatter (Rights reserved)
Strategies to verify equimolar peptide release in mass spectrometry-based protein quantification exemplified for apolipoprotein (a) / van der Burgt, Yuri E.M. (CC BY)
Progranulin measurement with a new automated method: a step forward in the diagnostic approach to neurodegenerative disorders / Cosma, Chiara (Rights reserved)
The biological variation of insulin resistance markers: data from the European Biological Variation Study (EuBIVAS) / Carobene, Anna (Rights reserved)
Evaluation of current indirect methods for measuring LDL-cholesterol / Drobnik, Sophia (Rights reserved)
Manual tilt tube method for prothrombin time: a commentary on contemporary relevance / Favaloro, Emmanuel J. (Rights reserved)
Blood samples for ammonia analysis do not require transport to the laboratory on ice: a study of ammonia stability and cause of in vitro ammonia increase in samples from patients with hyperammonaemia / Mercer-Smith, Gavin W. (Rights reserved)
Capillary blood parameters are gestational age, birthweight, delivery mode and gender dependent in healthy preterm and term infants / Perrotta, Marika (Rights reserved)
Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase / Knörnschild, Franz L. (Rights reserved)
Correction of negative-interference from calcium dobesilate in the Roche sarcosine oxidase creatinine assay using CuO / Zhao, Meng (Rights reserved)
PLENARY LECTURE 4 - Digital Twins: from Personalised Medicine to Precision Public Health. (Rights reserved)
Preservation of urine specimens for metabolic evaluation of recurrent urinary stone formers / Šálek, Tomáš (CC BY)
The correlation between serum angiopoietin-2 levels and acute kidney injury (AKI): a meta-analysis / Zhang, Juncheng (Rights reserved)
Performance evaluation of enzymatic total bile acid (TBA) routine assays: systematic comparison of five fifth-generation TBA cycling methods and their individual bile acid recovery from HPLC-MS/MS reference / Grimmler, Matthias (CC BY)
SYMPOSIUM 1 - New approaches for deriving and applying biological variation data for clinical use (Rights reserved)
ROUND-TABLE 3 - Emerging AI Applications in Laboratory Medicine (Rights reserved)
Reference, calibration and referral laboratories – a look at current European provisions and beyond / Buchta, Christoph (Rights reserved)
Is sweat conductivity still a relevant screening test for cystic fibrosis? Participation over 10 years / Robbins, Natasha (CC BY)
Setting analytical performance specification by simulation (Milan model 1b) / Low, Hui Qi (Rights reserved)
The information about the metrological traceability pedigree of the in vitro diagnostic calibrators should be improved: the case of plasma ethanol / Capoferri, Alessia (Rights reserved)
Serum free light chains reference intervals for the Lebanese population / El Karaaoui, Abdulkarim (Rights reserved)
Blood self-sampling: friend or foe? / Plebani, Mario (Rights reserved)
EFLM SYMPOSIUM 1 - EFLM - BioMedAlliance - Laboratory Medicine and the EU in the Era of Precision Medicine (Rights reserved)
Analytical performance evaluation and optimization of serum 25 (OH) D LC-MS/MS measurement / Zhou, Weiyan (Rights reserved)
Neonatal reference intervals for serum steroid hormone concentrations measured by LC-MS/MS / Olthof, Anouk (CC BY)
How do experts determine where to intervene on test ordering? An interview study / Podolsky, Eyal (Rights reserved)
External quality assessment of the manual tilt tube technique for prothrombin time testing: a report from the IFCC-SSC/ISTH Working Group on the Standardization of PT/INR / van Rijn, Claudia (CC BY)
OPENING LECTURE - Human Health and Well-being: Balancing Between Flavor and Gut Microbiota (Rights reserved)
Diagnostic performance of Mindray CL1200i high sensitivity cardiac troponin I assay compared to Abbott Alinity cardiac troponin I assay for the diagnosis of type 1 and 2 acute myocardial infarction in females and males: MERITnI study / Apple, Fred S. (Rights reserved)
Blood self-sampling devices: innovation, interpretation and implementation in total lab automation / Poland, Dennis C.W. (CC BY)
Atypical cells in urine sediment: a novel biomarker for early detection of bladder cancer / Wang, Yinling (Rights reserved)
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA) / Buchta, Christoph (Rights reserved)
Evaluation of performance in preanalytical phase EQA: can laboratories mitigate common pitfalls? / Linko-Parvinen, Anna (Rights reserved)
An untargeted metabolomics approach to evaluate enzymatically deconjugated steroids and intact steroid conjugates in urine as diagnostic biomarkers for adrenal tumors / Vogg, Nora Johanna (Rights reserved)
Plasmacytoid dendritic cell proliferation and acute myeloid leukemia with minimal differentiation (AML-M0) / Yang, Suwen (Rights reserved)
Frontmatter (Rights reserved)
Assessment of canonical diurnal variations in plasma glucose using quantile regression modelling and Chronomaps / Porsch-Özçürümez, Mustafa Kemal (Rights reserved)
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA) / Buchta, Christoph (Rights reserved)
Implications of monoclonal gammopathy and isoelectric focusing pattern 5 on the free light chain kappa diagnostics in cerebrospinal fluid / Hannich, Malte J. (Rights reserved)
Expanded carrier screening for 224 monogenic disease genes in 1,499 Chinese couples: a single-center study / Tan, Jianxin (Rights reserved)
Evaluation of revised UK-NEQAS CSF-xanthochromia method for subarachnoid hemorrhage: outcome data provide evidence for clinical value / Sam, Khin Moe (Rights reserved)
Sigma metric is more correlated with analytical imprecision than bias / Low, Hui Qi (Rights reserved)
Establishment of gender– and age–related reference intervals for serum uric acid in adults based on big data from Zhejiang Province in China / Chen, Dandan (Rights reserved)
Refining within-subject biological variation estimation using routine laboratory data: practical applications of the refineR algorithm / Røys, Eirik Åsen (CC BY)
The neglected issue of pyridoxal- 5′ phosphate / Plebani, Mario (Rights reserved)
The journey to pre-analytical quality / Plebani, Mario (CC BY)
The EuroFlow PIDOT external quality assurance scheme: enhancing laboratory performance evaluation in immunophenotyping of rare lymphoid immunodeficiencies / Neirinck, Jana (Rights reserved)
Salivary fatty acids in humans: a comprehensive literature review / Abodi, Martina (CC BY)
A standard to report biological variation data studies – based on an expert opinion / Bartlett, William A. (Rights reserved)
Liquid biopsy in oncology: navigating technical hurdles and future transition for precision medicine / Xie, Mengxiao (CC BY)
Kidney diseases and transplantation, urinalysis, urinary biomarkers (Rights reserved)
EFLM Task Force Preparation of Labs for Emergencies (TF-PLE) recommendations for reinforcing cyber-security and managing cyber-attacks in medical laboratories / Lippi, Giuseppe (Rights reserved)
Krebs von den Lungen-6 (KL-6) as a diagnostic and prognostic biomarker for non-neoplastic lung diseases / Achille, Alessia (Rights reserved)
Urgent need to adopt age-specific TSH upper reference limit for the elderly – a position statement of the Belgian thyroid club / Benamour, Meryem (Rights reserved)
A falsely elevated blood alcohol concentration (BAC) related to an intravenous administration of phenytoin sodium / Leuger, Laurent (Rights reserved)
IFCC SYMPOSIUM 1 - Hot topics in Laboratory Medicine (Rights reserved)
SYMPOSIUM 11 - Quality Assurance in Autoimmunity (Rights reserved)
Evidence for stability of cardiac troponin T concentrations measured with a high sensitivity TnT test in serum and lithium heparin plasma after six-year storage at −80 °C and multiple freeze-thaw cycles / Henricks, Linda M. (CC BY)
Venous blood collection systems using evacuated tubes: a systematic review focusing on safety, efficacy and economic implications of integrated vs. combined systems / Rigoni, Marta (CC BY)
Strengthening international cooperation and confidence in the field of laboratory medicine by ISO standardization / Spitzenberger, Folker (Rights reserved)
New generation of Abbott enzyme assays: imprecision, methods comparison, and impact on patients’ results / Chévrier, Marc (Rights reserved)
CD34+ progenitor cells meet metrology / Brando, Bruno (Rights reserved)
10 th Annual Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry (ÖGLMKC) (Rights reserved)
Evaluation of the clinical performance of anti-mutated citrullinated vimentin antibody and 14-3-3 eta testing in rheumatoid arthritis / Nelson, Heather A. (Rights reserved)
A value-based score for clinical laboratories: promoting the work of the new EFLM committee / Plebani, Mario (CC BY)
Copeptin as a diagnostic and prognostic biomarker in pediatric diseases / Shu, Xiaoli (Rights reserved)
Reply to “Is this quantitative test fit-for-purpose?” / Lord, Sarah J. (CC BY)
Beyond test results: the strategic importance of metadata for the integration of AI in laboratory medicine / Del Ben, Fabio (Rights reserved)
SYMPOSIUM 14 - Integrating Recent Basic Biomolecular Achievements in Medical Practice - Diagnostics & Therapy (Rights reserved)
Evolution of autoimmune diagnostics over the past 10 years: lessons learned from the UK NEQAS external quality assessment EQA programs / Garrafa, Emirena (Rights reserved)
Recommendations for European laboratories based on the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease / Cavalier, Etienne (Rights reserved)
Clinical applications of circulating tumor cell detection: challenges and strategies / Ma, Chunhui (Rights reserved)
Vancomycin assay interference: low-level IgM paraprotein disrupts Siemens Atellica ® CH VANC assay / De koninck, Stijn (Rights reserved)
Two cases of MTHFR C677T polymorphism typing failure by Taqman system due to MTHFR 679 GA heterozygous mutation / Che, Guanglu (Rights reserved)
Data flow in clinical laboratories: could metadata and peridata bridge the gap to new AI-based applications? / Padoan, Andrea (CC BY)
Targeted MRM-analysis of plasma proteins in frozen whole blood samples from patients with COVID-19: a retrospective study / Bugrova, Anna E. (Rights reserved)
The different serum albumin assays influence calcium status in haemodialysis patients: a comparative study against free calcium as a reference method / Eisa, Osama (Rights reserved)
Evidence-based assessment of the application of Six Sigma to infectious disease serology quality control / Dimech, Wayne (CC BY)
Determining the minimum blood volume required for laboratory testing in newborns / Cadamuro, Janne (Rights reserved)
The potential role of leukocytes cell population data (CPD) for diagnosing sepsis in adult patients admitted to the intensive care unit / Roccaforte, Vincenzo (Rights reserved)
Reference intervals and percentiles for soluble transferrin receptor and sTfR/log ferritin index in healthy children and adolescents / Prenzel, Freerk (Rights reserved)
Concordance between the updated Elecsys cerebrospinal fluid immunoassays and amyloid positron emission tomography for Alzheimer’s disease assessment: findings from the Apollo study / Schinke, Henrik (CC BY)
A physio-chemical mathematical model of the effects of blood analysis delay on acid-base, metabolite and electrolyte status: evaluation in blood from critical care patients / Nevirian, Bahareh (Rights reserved)
Neonatal and paediatric laboratory medicine, including prenatal testing (Rights reserved)
Metabolic diseases (Rights reserved)
Exploring the extent of post-analytical errors, with a focus on transcription errors – an intervention within the VIPVIZA study / Mickelsson, Malin (CC BY)
Reference Intervals: Direct/Indirect; population vs personal reference intervals (Rights reserved)
Frontmatter (Rights reserved)
Guidelines for the correct use of the nomenclature of biochemical indices of bone status: a position statement of the Joint IOF Working Group and IFCC Committee on Bone Metabolism / Lombardi, Giovanni (Rights reserved)
Diagnostic performance of specific biomarkers for interstitial lung disease: a single center study / Maharjan, Anu S. (Rights reserved)
Quality indicators for urine sample contamination: can squamous epithelial cells and bacteria count be used to identify properly collected samples? / Walber, Gabriela Blauth (Rights reserved)
Impact of delayed centrifugation on the stability of 32 biochemical analytes in blood samples collected in serum gel tubes and stored at room temperature / Sanz-Felisi, María (Rights reserved)
Not all biases are created equal: how to deal with bias on laboratory measurements / Panteghini, Mauro (Rights reserved)
Iron deficiency and iron deficiency anemia in transgender populations: what’s different? / Azzellino, Gianluca (Rights reserved)
Point of Care testing, critical care, emergency medicine (Rights reserved)
Impact of biological and genetic features of leukemic cells on the occurrence of “shark fins” in the WPC channel scattergrams of the Sysmex XN hematology analyzers in patients with chronic lymphocytic leukemia / Egger, Margot (CC BY)
Antiphospholipid IgG Certified Reference Material ERM ® -DA477/IFCC: a tool for aPL harmonization? / Grossi, Claudia (CC BY)
Unveiling the power of R: a comprehensive perspective for laboratory medicine data analysis / Ma, Chaochao (Rights reserved)
A simple gatekeeping intervention improves the appropriateness of blood urea nitrogen testing / Devis, Luigi (CC BY)
Are the benefits of External Quality Assessment (EQA) recognized beyond the echo chamber? / MacKenzie, Finlay (Rights reserved)
SYMPOSIUM 13 - Value of Diagnostics and Labtest around NCDs (Rights reserved)
Data Science, Digital health, big data and smart technologies (Rights reserved)
Novel protocol for metabolomics data normalization and biomarker discovery in human tears / Serrano-Marín, Joan (CC BY)
Evaluation of serum NFL, T-tau, p-tau181, p-tau217, Aβ40 and Aβ42 for the diagnosis of neurodegenerative diseases / Kahouadji, Samy (Rights reserved)
Six Sigma in laboratory medicine: the unfinished symphony / Coskun, Abdurrahman (Rights reserved)
Geriatric testing (Rights reserved)
Evaluation of the analytical and clinical performance of a high-sensitivity troponin I point-of-care assay in the Mersey Acute Coronary Syndrome Rule Out Study (MACROS-2) / Dakshi, Ahmed (Rights reserved)
External quality assessment-based tumor marker harmonization simulation; insights in achievable harmonization for CA 15-3 and CEA / Van Rossum, Huub H. (Rights reserved)
Patient risk management in laboratory medicine: an international survey to assess the severity of harm associated with erroneous reported results / Peltier, Lucas (CC BY)
Imlifidase: a new interferent on serum protein electrophoresis looking as a rare plasma cell dyscrasia / Davanzo, Veronica (CC BY)
Test Evaluation, outcome studies, clinical utility of biomarkers (Rights reserved)
Targeted proteomics of serum IGF-I, -II, IGFBP-2, -3, -4, -5, -6 and ALS / Albrethsen, Jakob (Rights reserved)
Neutralizing antibodies against KP.2 and KP.3: why the current vaccine needs an update / Gillot, Constant (CC BY)
ROUND-TABLE 1 - Beyond the Numbers: Integrating Laboratory and Clinical Perspectives on Thyroid Health (Rights reserved)
Evidence based medicine, including Guidelines (Rights reserved)
Toxicology and TDM (Rights reserved)
Synovial fluid D-lactate – a pathogen-specific biomarker for septic arthritis: a prospective multicenter study / Karbysheva, Svetlana (Rights reserved)
Cell population data for early detection of sepsis in patients with suspected infection in the emergency department / Cancella De Abreu, Marta (Rights reserved)
“Activation” of macro-AST by pyridoxal-5-phosphate in the assay for aspartate aminotransferase / Fermon, Erica J. (Rights reserved)
SYMPOSIUM 5 - Sustainable Reference intervals and Clinical Decision Limits: Towards Standardization & Harmonization (Rights reserved)
Emerging & Analytical technologies, applications and limitations (Rights reserved)
Frontmatter (Rights reserved)
Others (Rights reserved)
How has the external quality assessment/proficiency testing of semen analysis been developed in the past 34 years: a review / Zheng, Yan (Rights reserved)
What does cancer screening have to do with tomato growing? / Chatanaka, Miyo K. (Rights reserved)
Clinical utility of personalized reference intervals for CEA in the early detection of oncologic disease / Martínez-Espartosa, Débora (Rights reserved)
Accurate non-ceruloplasmin bound copper: a new biomarker for the assessment and monitoring of Wilson disease patients using HPLC coupled to ICP-MS/MS / Harrington, Chris F. (Rights reserved)
SYMPOSIUM 8 - Current and Future Landscape of Tumor Markers in Clinical Use: Applications, Challenges, and Perspectives (Rights reserved)
Metrological traceability and test standardization/harmonization (Rights reserved)
Point-of-care testing improves care timeliness in the emergency department. A multicenter randomized clinical trial (study POCTUR) / Leon-Justel, Antonio (Rights reserved)
Colorimetric correcting for sample concentration in stool samples / Delanghe, Joris R. (Rights reserved)
Temporal dynamics in laboratory medicine: cosinor analysis and real-world data (RWD) approaches to population chronobiology / Marques-Garcia, Fernando (Rights reserved)
Current trends and future projections in the clinical laboratory test market: implications for resource management and strategic planning / Lippi, Giuseppe (Rights reserved)
Biochemical evidence of vitamin B12 deficiency: a crucial issue to address supplementation in pregnant women / Ferraro, Simona (Rights reserved)
ROUND-TABLE 2 - Health Economics: Transforming Laboratory Data into Value (Rights reserved)
Genetic diseases (Rights reserved)
Agreement of lymphocyte subsets detection permits reference intervals transference between flow cytometry systems: direct validation using established reference intervals / Liu, Mei (Rights reserved)
Estimation of the allowable total error of the absolute CD34+ cell count by flow cytometry using data from UK NEQAS exercises 2004–2024 / Brando, Bruno (CC BY)
Comparison between monotest and traditional batch-based ELISA assays for therapeutic drug monitoring of infliximab and adalimumab levels and anti-drug antibodies / Moneo, Mikel (CC BY)
EFLM Task Force Preparation of Labs for Emergencies (TF-PLE) survey on cybersecurity / Lippi, Giuseppe (Rights reserved)
Evaluating the accuracy of ChatGPT in classifying normal and abnormal blood cell morphology / Negrini, Davide (Rights reserved)
Analytical verification of the Atellica VTLi point of care high sensitivity troponin I assay / Florkowski, Christopher M. (CC BY)
The first case of Teclistamab interference with serum electrophoresis and immunofixation / Kadkhoda, Kamran (Rights reserved)
Supporting prioritization efforts of higher-order reference providers using evidence from the Joint Committee for Traceability in Laboratory Medicine database / Panteghini, Mauro (Rights reserved)
Health literacy: a new challenge for laboratory medicine / Pennestrì, Federico (Rights reserved)
Advancing value-based laboratory medicine / Plebani, Mario (Rights reserved)
Is this quantitative test fit-for-purpose? / Åsberg, Arne (Rights reserved)
Cascading referencing of terms and definitions / Buchta, Christoph (Rights reserved)
SYMPOSIUM 2 - The present and future of minimal residual disease (MRD) assessment (Rights reserved)
SYMPOSIUM 9 - Biomarkers of the Brain: Past and Future (Rights reserved)
Tumor specific protein 70 targeted tumor cell isolation technology can improve the accuracy of cytopathological examination / Zhang, Lixia (Rights reserved)
Analytical and clinical evaluations of Snibe Maglumi ® S100B assay / Kahouadji, Samy (Rights reserved)
Failing methemoglobin blood gas analyses in a sodium nitrite intoxication / Van Heuverswyn, Jasper (Rights reserved)
Advancements and challenges in high-sensitivity cardiac troponin assays: diagnostic, pathophysiological, and clinical perspectives / Clerico, Aldo (Rights reserved)
An immuno-DOT diagnostic assay for autoimmune nodopathy / Jentzer, Alexandre (Rights reserved)
Evaluation of pre-analytical factors impacting urine test strip and chemistry results / Bohn, Mary Kathryn (Rights reserved)
Pleural effusion as a sample matrix for laboratory analyses in cancer management: a perspective / Spisarová, Martina (Rights reserved)
Misdiagnosis of type 2B von Willebrand disease as immune thrombocytopenia in a thrombocytopenic patient / Lu, Xiaodong (Rights reserved)
Diagnostic challenge between a frequent polygenic hypocholesterolemia and an unusual Smith Lemli Opitz syndrome related to bi-allelic DHCR7 mutations / Bonnot Ruget, Mathilde (Rights reserved)
The value of Sigma-metrics in laboratory medicine / Bayat, Hassan (Rights reserved)
QC Constellation: a cutting-edge solution for risk and patient-based quality control in clinical laboratories / Çubukçu, Hikmet Can (Rights reserved)
56 th National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC – Laboratory Medicine) (Rights reserved)
Sharing reference intervals and monitoring patients across laboratories – findings from a likely commutable external quality assurance program / Farrell, Christopher J.L. (Rights reserved)
Reference intervals of circulating secretoneurin concentrations determined in a large cohort of community dwellers: the HUNT study / Aakre, Kristin M. (CC BY)
Cerebrospinal fluid kappa free light chains in patients with tumefactive demyelination / Banks, Samantha A. (Rights reserved)
Assessing post-analytical phase harmonization in European laboratories: a survey promoted by the EFLM Working Group on Harmonization / Zaninotto, Martina (Rights reserved)
Blood-based biomarkers in Alzheimer’s disease – moving towards a new era of diagnostics / Arslan, Burak (CC BY)
Data mining of reference intervals for serum creatinine: an improvement in glomerular filtration rate estimating equations based on Q-values / Ma, Yao (Rights reserved)
Falsely decreased Abbott Alinity-c gamma-glutamyl transferase-2 result from paraprotein and heparin interference: case report and subsequent laboratory experiments / Sam, Khin M. (Rights reserved)
Harmonizing the post-analytical phase: focus on the laboratory report / Plebani, Mario (CC BY)
Circulating tumor DNA measurement: a new pillar of medical oncology? / Melichar, Bohuslav (Rights reserved)
How clinical laboratories select and use Analytical Performance Specifications (APS) in Italy / Ceriotti, Ferruccio (Rights reserved)
Multivariate anomaly detection models enhance identification of errors in routine clinical chemistry testing / Farrell, Christopher J.L. (Rights reserved)
To rule-in, or not to falsely rule-out, that is the question: evaluation of hs-cTnT EQA performance in light of the ESC-2020 guideline / van Schrojenstein Lantman, Marith (CC BY)
Exploring evolutionary trajectories in ovarian cancer patients by longitudinal analysis of ctDNA / Kutz, Oliver (Rights reserved)
A reactive monocyte subset characterized by low expression of CD91 is expanded during sterile and septic inflammation / Gosset, Christian (Rights reserved)
Evaluation of effects from hemoglobin variants on HbA 1c measurements by different methods / Song, Yichuan (Rights reserved)
Comprehensive analysis and clinical case studies on pseudoeosinophilia: insights and implications – unraveling the complexity: analytical approaches and clinical significance / Hu, Yonggang (Rights reserved)
Tubular phosphate transport: a comparison between different methods of urine sample collection in FGF23-dependent hypophosphatemic syndromes / Arcidiacono, Gaetano Paride (CC BY)
Sharing reference intervals and monitoring patients across laboratories – findings from a likely commutable external quality assurance program / Farrell, Christopher J.L. (Rights reserved)
Dynamic mirroring: unveiling the role of digital twins, artificial intelligence and synthetic data for personalized medicine in laboratory medicine / Padoan, Andrea (CC BY)
Novel thiopurine S-methyltransferase (TPMT) variant identified in Malay individuals / Lee, Chun Kiat (Rights reserved)
The routine coagulation assays plasma stability – in the wake of the new European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) biological variability database / Kuktić, Ivona (Rights reserved)
Comparison of a two-step Tempus600 hub solution single-tube vs. container-based, one-step pneumatic transport system / Luginbühl, Marc (Rights reserved)
Diagnostic value of quantitative chemiluminescence immunoassay for anti-gp210 and anti-sp100 antibodies in primary biliary cholangitis / Zhang, Yazhen (Rights reserved)
Using Bland-Altman plot-based harmonization algorithm to optimize the harmonization for immunoassays / Fang, Huiling (Rights reserved)
Diurnal and day-to-day biological variation of salivary cortisol and cortisone / Danese, Elisa (Rights reserved)
CX3CL1/Fractalkine as a biomarker for early pregnancy prediction of preterm premature rupture of membranes / Kahouadji, Samy (Rights reserved)
Accurate predictory role of monocyte distribution width on short-term outcome in sepsis patients / Peng, Lan (Rights reserved)
Improving HCV diagnosis following a false-negative anti-HCV result / Long, Xia (Rights reserved)
Serum biomarkers of inflammation and vascular damage upon SARS-Cov-2 mRNA vaccine in patients with thymic epithelial tumors / Cernera, Gustavo (CC BY)
New reimbursement models to promote better patient outcomes and overall value in laboratory medicine and healthcare / Trenti, Tommaso (Rights reserved)
Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study / Scarlata, Simone (Rights reserved)
Can we identify patients carrying targeted deleterious DPYD variants with plasma uracil and dihydrouracil? A GPCO-RNPGx retrospective analysis / Launay, Manon (Rights reserved)
Quantification of C1 inhibitor activity using a chromogenic automated assay: analytical and clinical performances / Renaudineau, Yves (Rights reserved)
A comparative evaluation of the analytical performances of premier resolution-high-performance liquid chromatography (PR-HPLC) with capillary zone electrophoresis (CZE) assays for the detection of hemoglobin variants and the quantitation of HbA 0, A 2, E, and F / Laksap, Sirikwan (Rights reserved)
Setting analytical performance specifications for copeptin-based testing / Choy, Kay Weng (Rights reserved)
Frontmatter (Rights reserved)
A vision to the future: value-based laboratory medicine / Plebani, Mario (Rights reserved)
Diagnostic performance of a point of care high-sensitivity cardiac troponin I assay and single measurement evaluation to rule out and rule in acute coronary syndrome / De Iuliis, Vincenzo (Rights reserved)
Evaluating the HYDRASHIFT 2/4 Daratumumab assay: a powerful approach to assess treatment response in multiple myeloma / Lee, Hyun-Woo (CC BY)
Stability of steroid hormones in dried blood spots (DBS) / Olthof, Anouk (CC BY)
Issues in assessing analytical performance specifications in healthcare systems assembling multiple laboratories and measuring systems / Theodorsson, Elvar (Rights reserved)
Reply to: “Is uracil enough for effective pre-emptive DPD testing?” / Thomas, Fabienne (Rights reserved)
Assessment of accuracy of laboratory testing results, relative to peer group consensus values in external quality control, by bivariate z-score analysis: the example of D-Dimer / Meijer, Piet (CC BY)
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine-10,11-epoxide in human serum and plasma / Schierscher, Tobias (CC BY)
Evolution of acquired haemoglobin H disease monitored by capillary electrophoresis: a case of a myelofibrotic patient with a novel ATRX mutation / Rosetti, Marco (Rights reserved)
Inadvertent omission of a specimen integrity comment – an overlooked post-analytical error / Bowen, Raffick A.R. (Rights reserved)
The role of analytical performance specifications in international guidelines and standards dealing with metrological traceability in laboratory medicine / Greg Miller, W. (CC BY)
ISMD2024 Thirteenth International Symposium on Molecular Diagnostics (Rights reserved)
Comparison of ChatGPT, Gemini, and Le Chat with physician interpretations of medical laboratory questions from an online health forum / Meyer, Annika (CC BY)
Reference values for plasma and urine trace elements in a Swiss population-based cohort / Perrais, Maïwenn (Rights reserved)
Stability of ten serum tumor markers after one year of storage at −18°C / Mondésert, Etienne (Rights reserved)
SARS-CoV-2 is here to stay: do not lower our guard / Lippi, Giuseppe (Rights reserved)
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of phenobarbital in human serum and plasma / Schierscher, Tobias (CC BY)
Analytical evaluation of the novel Mindray high sensitivity cardiac troponin I immunoassay on CL-1200i / Lippi, Giuseppe (Rights reserved)
The correlation of urea and creatinine concentrations in sweat and saliva with plasma during hemodialysis: an observational cohort study / Adelaars, Sophie (CC BY)
Analytical performance specifications for combined uncertainty budget in the implementation of metrological traceability / Panteghini, Mauro (Rights reserved)
Is uracil enough for effective pre-emptive DPD testing? / Heersche, Niels (CC BY)
Recommendations for blood sampling in emergency departments from the European Society for Emergency Medicine (EUSEM), European Society for Emergency Nursing (EuSEN), and European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase. Executive summary / Garcia-Castrillo, Luis (Rights reserved)
Smartphone swabs as an emerging tool for toxicology testing: a proof-of-concept study in a nightclub / Willeman, Théo (Rights reserved)
Point-of-care testing, near-patient testing and patient self-testing: warning points / Banfi, Giuseppe (Rights reserved)
Validation of the enhanced liver fibrosis (ELF)-test in heparinized and EDTA plasma for use in reflex testing algorithms for metabolic dysfunction-associated steatotic liver disease (MASLD) / van Son, Koen C. (CC BY)
Value of plasma neurofilament light chain for monitoring efficacy in children with later-onset spinal muscular atrophy under nusinersen treatment / Jin, Jianing (Rights reserved)
Computational pathology: an evolving concept / Prassas, Ioannis (Rights reserved)
Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes / Balderacchi, Alice M. (Rights reserved)
Impact of hemolysis on uracilemia in the context of dihydropyrimidine dehydrogenase deficiency testing / Loison, Gaspard (CC BY)
Inaccurate definition of Bence Jones proteinuria in the EFLM Urinalysis Guideline 2023 / Mussap, Michele (Rights reserved)
Expert-level detection of M-proteins in serum protein electrophoresis using machine learning / Elfert, Eike (Rights reserved)
Add-on testing: stability assessment of 63 biochemical analytes in centrifuged and capped samples stored at 16 °C / Nielsen, Anne J. (Rights reserved)
Facing the new IVD Regulation 2017/746: Contract Research Organizations (CROs), key partners of IVDs manufacturers for compliance / Kali, Sabrina (Rights reserved)
Frontmatter (Rights reserved)
The impact of physiological variations on personalized reference intervals and decision limits: an in-depth analysis / Coskun, Abdurrahman (Rights reserved)
HTA model for laboratory medicine technologies: overview of approaches adopted in some international agencies / d’Angela, Daniela (Rights reserved)
Frontmatter (Rights reserved)
Neurofilament light protein as a biomarker for spinal muscular atrophy: a review and reference ranges / Bayoumy, Sherif (CC BY)
Molecular allergology: a clinical laboratory tool for precision diagnosis, stratification and follow-up of allergic patients / Giusti, Delphine (Rights reserved)
Validation and verification framework and data integration of biosensors and in vitro diagnostic devices: a position statement of the IFCC Committee on Mobile Health and Bioengineering in Laboratory Medicine (C-MBHLM) and the IFCC Scientific Division / Gruson, Damien (Rights reserved)
An automated workflow based on data independent acquisition for practical and high-throughput personalized assay development and minimal residual disease monitoring in multiple myeloma patients / Wijnands, Charissa (CC BY)
The CoLab score is associated with SARS-CoV-2 viral load during admission in individuals admitted to the intensive care unit: the CoLaIC cohort study / Schoenmakers, Tom (CC BY)
Analytical validation of the Mindray CL1200i analyzer high sensitivity cardiac troponin I assay: MERITnI study / Fabre-Estremera, Blanca (Rights reserved)
Assessment of the 2023 European Kidney Function Consortium (EKFC) equations in a Chinese adult population / Chen, Yi (Rights reserved)
Frontmatter (Rights reserved)
Fetal chronic hypoxia does not affect urinary presepsin levels in newborns at birth / D’Adamo, Ebe (Rights reserved)
Targeted ultra performance liquid chromatography tandem mass spectrometry procedures for the diagnosis of inborn errors of metabolism: validation through ERNDIM external quality assessment schemes / Oliva, Clara (Rights reserved)
Reference intervals for high sensitivity cardiac troponin I and N-terminal pro-B-type natriuretic peptide in children and adolescents on the Siemens Atellica / Ameh, Akoji (Rights reserved)
The 10+1 Santorini Conference (Rights reserved)
Get reliable laboratory findings – how to recognize the deceptive effects of angiotensin-converting enzyme inhibitor therapy in the laboratory diagnostics of sarcoidosis? / Szabó, Attila Ádám (CC BY)
Bilirubin measurements in neonates: uniform neonatal treatment can only be achieved by improved standardization / Hulzebos, Christian V. (CC BY)
The EFLM European Urinalysis Guideline 2023 / Kouri, Timo T. (Rights reserved)
Circulating tumor DNA methylation: a promising clinical tool for cancer diagnosis and management / Wang, Binliang (Rights reserved)
Time-dependent characteristics of analytical measurands / Porsch-Özçürümez, Mustafa Kemal (Rights reserved)
Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes / Balderacchi, Alice M. (Rights reserved)
Monocyte distribution width (MDW): study of reference values in blood donors / García-Álvarez, Ana (CC BY)
Familial dysalbuminemic hyperthyroxinemia coexisting with a Grave’s disease: a Belgian case report / Wolff, Fleur (Rights reserved)
Serum vitamin B12 levels during chemotherapy against diffuse large B-cell lymphoma: a case report and review of the literature / Wang, Fang (Rights reserved)
Frontmatter (Rights reserved)
Analytical and diagnostic performance of Theradiag i-Tracker assays on IDS-iSYS for infliximab and adalimumab therapeutic drug monitoring / Herroelen, Pauline (Rights reserved)
Long-term effects of interventions applied to optimize the use of 25-OH vitamin D tests in primary health care / Lillo, Serena (CC BY)
Reference intervals of 24 trace elements in blood, plasma and erythrocytes for the Slovenian adult population / Štiglic, Alenka France (CC BY)
15th National Congress of the Portuguese Society of Clinical Chemistry, Genetics and Laboratory Medicine (Rights reserved)
Linearity assessment: deviation from linearity and residual of linear regression approaches / Lim, Chun Yee (Rights reserved)
Variations in tumor growth, intra-individual biological variability, and the interpretation of changes / Trapé, Jaume (Rights reserved)
OILVEQ: an Italian external quality control scheme for cannabinoids analysis in galenic preparations of cannabis oil / Rotolo, Maria Concetta (Rights reserved)
Verification of bile acid determination method and establishing reference intervals for biochemical and haematological parameters in third-trimester pregnant women / Zorić, Lara (Rights reserved)
An outline of measurement uncertainty of total protein in urine estimated according to the ISO Technical Specification 20914 / Borrillo, Francesca (Rights reserved)
EFLM European Urinalysis Guideline / Langlois, Michel R. (Rights reserved)
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays / Fazeli, Badrieh (CC BY)
Elevated S100B urine levels predict seizures in infants complicated by perinatal asphyxia and undergoing therapeutic hypothermia / Bersani, Iliana (Rights reserved)
Vitamin D and vitamin K status in postmenopausal women with normal and low bone mineral density / Zelzer, Sieglinde (Rights reserved)
Interaction of heparin with human cardiac troponin complex and its influence on the immunodetection of troponins in human blood samples / Riabkova, Natalia S. (CC BY)
Patients with antiphospholipid syndrome and a first venous or arterial thrombotic event: clinical characteristics, antibody profiles and estimate of the risk of recurrence / Pengo, Vittorio (CC BY)
Prognostic value of anti-SARS-CoV-2 antibodies: a systematic review / Mink, Sylvia (Rights reserved)
IgG and kappa free light chain CSF/serum indices: evaluating intrathecal immunoglobulin production in HIV infection in comparison with multiple sclerosis / Hagberg, Lars (CC BY)
Early diagnosis of severe illness in an outpatient – the Sysmex XN’s neutrophil reactivity parameter / Costa, Ruben M. (Rights reserved)
Report from the HarmoSter study: different LC-MS/MS androstenedione, DHEAS and testosterone methods compare well; however, unifying calibration is a double-edged sword / Fanelli, Flaminia (CC BY)
Nitrous oxide abuse direct measurement for diagnosis and follow-up: update on kinetics and impact on metabolic pathways / Lucas, Angèle (Rights reserved)
Evaluation of inflammatory biomarkers and vitamins in hospitalized patients with SARS-CoV-2 infection and post-COVID syndrome / Krčmová, Lenka Kujovská (Rights reserved)
In vitro, in vivo metabolism and quantification of the novel synthetic opioid N-piperidinyl etonitazene (etonitazepipne) / Berardinelli, Diletta (Rights reserved)
Reference intervals of circulating secretoneurin concentrations determined in a large cohort of community dwellers: the HUNT study / Aakre, Kristin M. (CC BY)
Six Sigma – is it time to re-evaluate its value in laboratory medicine? / Badrick, Tony (Rights reserved)
Analytical validation of the amplification refractory mutation system polymerase chain reaction-capillary electrophoresis assay to diagnose spinal muscular atrophy / Yao, Mei (Rights reserved)
A global perspective on the status of clinical metabolomics in laboratory medicine – a survey by the IFCC metabolomics working group / Fux, Elie (Rights reserved)
Considerations for applying emerging technologies in paediatric laboratory medicine / Lang, Tim (Rights reserved)
External quality assurance (EQA): navigating between quality and sustainability / Plebani, Mario (Rights reserved)
14th National Congress of the Portuguese Society of Clinical Chemistry, Genetics and Laboratory Medicine (Rights reserved)
Frontmatter (Rights reserved)
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of primidone in human serum and plasma / Schierscher, Tobias (CC BY)
Understanding the limitations of your assay using EQA data with serum creatinine as an example / Marrington, Rachel (CC BY)
Limitations of glycated albumin standardization when applied to the assessment of diabetes patients / Lenters-Westra, Erna (Rights reserved)
Crioplast ® is a reliable device to ensure pre-analytical stability of adrenocorticotrophin (ACTH) / Bosse, Maxime (Rights reserved)
Analytical evaluation of the Snibe β-isomerized C-terminal telopeptide of type I collagen (β-CTX-I) automated method / Gonzalez, Diego (Rights reserved)
Within- and between-subject biological variation estimates for the enumeration of lymphocyte deep immunophenotyping and monocyte subsets / Guo, Kai (Rights reserved)
Detection of urinary foam cells diagnosing the XGP with thrombopenia preoperatively: a case report / Guan, Shaonian (Rights reserved)
The final part of the CRESS trilogy – how to evaluate the quality of stability studies / Cornes, Michael (Rights reserved)
Outcome-based analytical performance specifications: current status and future challenges / Horvath, Andrea Rita (Rights reserved)
Minor head injury in anticoagulated patients: performance of biomarkers S100B, NSE, GFAP, UCH-L1 and Alinity TBI in the detection of intracranial injury. A prospective observational study / Menditto, Vincenzo G. (Rights reserved)
Spurious parathyroid hormone (PTH) elevation caused by macro-PTH / Lavalleye, Thibault (Rights reserved)
Six years of progress – highlights from the IFCC Emerging Technologies Division / Greaves, Ronda (CC BY)
Frontmatter (Rights reserved)
Improving protocols for α-synuclein seed amplification assays: analysis of preanalytical and analytical variables and identification of candidate parameters for seed quantification / Mammana, Angela (CC BY)
A high throughput immuno-affinity mass spectrometry method for detection and quantitation of SARS-CoV-2 nucleoprotein in human saliva and its comparison with RT-PCR, RT-LAMP, and lateral flow rapid antigen test / Lane, Dan (Rights reserved)
MALDI-MS in first-line screening of newborns for sickle cell disease: results from a prospective study in comparison to HPLC / El Osta, Marven (Rights reserved)
Improving protocols for α-synuclein seed amplification assays: analysis of preanalytical and analytical variables and identification of candidate parameters for seed quantification / Mammana, Angela (CC BY)
What the Milan conference has taught us about analytical performance specification model definition and measurand allocation / Panteghini, Mauro (Rights reserved)
Issues for standardization of neonatal bilirubinemia: a case of delayed phototherapy initiation / Vaubourdolle, Michel (Rights reserved)
Confounding factors of the expression of mTBI biomarkers, S100B, GFAP and UCH-L1 in an aging population / Calluy, Emma (CC BY)
Temporal biomarker concentration patterns during the early course of acute coronary syndrome / Eggers, Kai (CC BY)
Evaluation of effects from hemoglobin variants on HbA 1c measurements by different methods / Song, Yichuan (Rights reserved)
Should we depend on reference intervals from manufacturer package inserts? Comparing TSH and FT4 reference intervals from four manufacturers with results from modern indirect methods and the direct method / Dirks, Niek F. (CC BY)
Performance evaluation and user experience of BT-50 transportation unit with automated and scheduled quality control measurements / Tabata, Minori (CC BY)
Macroprolactin in mothers and their babies: what is its origin? / Nishiyama, Norito (Rights reserved)
Approaching sustainability in Laboratory Medicine / Thakur, Anjali (Rights reserved)
N-linked glycosylation of the M-protein variable region: glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma / Langerhorst, Pieter (CC BY)
Methemoglobinemia after sodium nitrite poisoning: what blood gas analysis tells us (and what it might not) / Cappellini, Fabrizio (Rights reserved)
Reply to: “Accurate predictory role of monocyte distribution width on short-term outcome in sepsis patients” / Liu, Yin (Rights reserved)
The role of Killer immunoglobulin-like receptors (KIRs) in the genetic susceptibility to non-celiac wheat sensitivity (NCWS) / Gambino, Caterina Maria (Rights reserved)
A comprehensive review on PFAS including survey results from the EFLM Member Societies / Ozben, Tomris (Rights reserved)
Potential medical impact of unrecognized in vitro hypokalemia due to hemolysis: a case series / Wu, Alan H.B. (CC BY)
Standardisation and harmonisation of thyroid-stimulating hormone measurements: historical, current, and future perspectives / Cowper, Ben (CC BY)
Analytical performance specifications based on biological variation data – considerations, strengths and limitations / Sandberg, Sverre (CC BY)
Blood over-testing: impact, ethical issues and mitigating actions / Pennestrì, Federico (Rights reserved)
Clinical Chemistry Laboratory Medicine in the post-acute COVID-19 era / Lippi, Giuseppe (Rights reserved)
AWMF statement on medical services in laboratory diagnostics and pathology with regard to the IVDR / Vogeser, Michael (Rights reserved)
Evaluation of analytical performance of AQUIOS CL flow cytometer and method comparison with bead-based flow cytometry methods / Chiron, Andrada S. (Rights reserved)
LC-MS/MS random access automation – a game changer for the 24/7 clinical laboratory / Greaves, Ronda (CC BY)
Navigating the path of reproducibility in microRNA-based biomarker research with ring trials / Sopić, Miron (CC BY)
Using analytical performance specifications in a medical laboratory / Jones, Graham Ross Dallas (Rights reserved)
Proteomic analysis of diabetic retinopathy identifies potential plasma-protein biomarkers for diagnosis and prognosis / Honoré, Bent (Rights reserved)
Monoclonal whole IgG impairs both fibrin and thrombin formation: hemostasis and surface plasmon resonance studies / Gonda, Lénárd (CC BY)
Enhanced patient-based real-time quality control using the graph-based anomaly detection / Shang, Xueling (Rights reserved)
The stability of 65 biochemistry analytes in plasma, serum, and whole blood / Zhou, Janet (Rights reserved)
Analytical performance specifications – moving from models to practical recommendations / Sandberg, Sverre (Rights reserved)
Frontmatter (Rights reserved)
Frontmatter (Rights reserved)
An automatic analysis and quality assurance method for lymphocyte subset identification / Zhang, MinYang (Rights reserved)
Screening for sickle cell disease: focus on newborn investigations / Mosca, Andrea (Rights reserved)
First reported co-occurrence of Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia with pseudo Chediak-Higashi anomaly and complex karyotype / An, Ziyi (Rights reserved)
Frontmatter (Rights reserved)
The influence of undetected hemolysis on POCT potassium results in the emergency department / Tintu, Andrei N. (CC BY)
When bias becomes part of imprecision: how to use analytical performance specifications to determine acceptability of lot-lot variation and other sources of possibly unacceptable bias / Thelen, Marc H.M. (Rights reserved)
Use of the term “Bence-Jones proteinuria” in the EFLM European Urinalysis Guideline 2023 / Kouri, Timo (Rights reserved)
Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China / Zhou, Weiyan (Rights reserved)
Targeted ultra performance liquid chromatography tandem mass spectrometry procedures for the diagnosis of inborn errors of metabolism: validation through ERNDIM external quality assessment schemes / Oliva, Clara (Rights reserved)
Association of prehospital lactate levels with base excess in various emergencies – a retrospective study / Eichinger, Michael (Rights reserved)
External quality assessment performance in ten countries: an IFCC global laboratory quality project / Bais, Renze (Rights reserved)
Are there any reasons to use three levels of quality control materials instead of two and if so, what are the arguments? / Sonntag, Oswald (CC BY)
Falsely elevated T 3 due to interference of anti-T 3 autoantibodies: a case report / Jin, Jing (Rights reserved)
Web-accessible critical limits and critical values for urgent clinician notification / Kost, Gerald J. (CC BY)
Biological matrices, reagents and turnaround-time: the full-circle of artificial intelligence in the pre-analytical Phase. Comment on Turcic A, et al., Machine learning to optimize cerebrospinal fluid dilution for analysis of MRZH reaction. CCLM 2024;62:436–41 / Ialongo, Cristiano (Rights reserved)
Quality control in the Netherlands; todays practices and starting points for guidance and future research / van Rossum, Huub H. (CC BY)
Skin in the game: a review of single-cell and spatial transcriptomics in dermatological research / Schepps, Samuel (Rights reserved)
Applying the Milan models to setting analytical performance specifications – considering all the information / Jones, Graham R.D. (Rights reserved)
Patient result monitoring of HbA 1c shows small seasonal variations and steady decrease over more than 10 years / Rollborn, Niclas (CC BY)
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms: a systematic review of the literature / Fernández-de-las-Peñas, César (Rights reserved)
An LC–MS/MS method for serum cystatin C quantification and its comparison with two commercial immunoassays / Zhang, Li (Rights reserved)
Stimulating thyrotropin receptor antibodies in early pregnancy / Uldall-Torp, Nanna Maria (Rights reserved)
State-of-the-art model for derivation of analytical performance specifications: how to define the highest level of analytical performance technically achievable / Borrillo, Francesca (Rights reserved)
Thyroglobulin measurement is the most powerful outcome predictor in differentiated thyroid cancer: a decision tree analysis in a European multicenter series / Giovanella, Luca (Rights reserved)
Disturbances of calcium, magnesium, and phosphate homeostasis: incidence, probable causes, and outcome / Malinowska, Justyna (Rights reserved)

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