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Periodical

Title:: Zeitschrift für Naturforschung

Other titles:: Zeitschrift für Naturforschung / C

Publication:: Berlin: de Gruyter

Note:: Gesehen am 09.07.24; Ersch. alle 2 Monate; 355!URL-Ä(25-03-24)

Scope:: Online-Ressource

ISSN:: 1865-7125

ZDB-ID:: 2078107-6

Previous Title:: Zeitschrift für Naturforschung / B. B, a @journal of chemical sciences

Keywords:: Biologie ; Zeitschrift ; Biochemie ; Zeitschrift ; Biophysik ; Zeitschrift ; Zeitschrift

Classification:: Naturwissenschaften

Collection:: Naturwissenschaften

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Article

Author:: Gonfa, Yilma Hunde; Bachheti, Archana; Semwal, Prabhakar; Rai, Nishant; Singab, Abdel Nasser; Bachheti, Rakesh Kumar

Title:: Hepatoprotective activity of medicinal plants, their phytochemistry, and safety concerns: a systematic review

Publication:: Berlin: de Gruyter, 2025

Language:: English

Information:: Abstract: Medicinal plants and their derivatives represent a promising reservoir of remedies for various ailments. Especially secondary metabolites of these plants, including alkaloids, flavonoids, phenolic compounds, terpenoids, steroids, saponins, tannins, and anthraquinones, play crucial roles in hepatoprotection. Studies have identified several prominent phytoconstituents, such as silymarin, quercetin, luteolin, glycyrrhizin, curcumin, gallic acid, chebulic acid, catechin, aloin, emodin, liquiritin, liquiritigenin, cudraflavone B, and karaviloside, as effective agents for addressing hepatotoxicity. The mechanisms underlying their efficacy include antioxidant, anti-inflammatory, free radical scavenging, and the ability to block oxidative stress, cytokine production, and stabilize liver cell membranes. The application of natural products derived from medicinal plants in treating liver injuries is rooted in their efficacy, cost-effectiveness, and safety profile, contributing to their popularity. Many studies, encompassing in vitro, in vivo, preclinical, and clinical investigations, have demonstrated that the extracts of medicinal plants mitigate chemical-induced liver damage using animal models. However, intensive research efforts regarding the safety, regulatory standard, and quality control issues for using medicinal plants as hepatoprotective agents remain the strong task of scholars. The primary focus of this systematic review is to analyze the current state of the literature regarding treating liver ailments using extracts from medicinal plants, examining their phytochemical composition, and addressing associated safety considerations.

Scope:: Online-Ressource

Note:: Kein Open Access; Archivierung/Langzeitarchivierung gewährleistet

Keywords:: hepatoprotective activity ; medicinal plants ; phytochemistry ; safety concerns

Classification:: Naturwissenschaften; Sonstiges

URN:: urn:nbn:de:101:1-2503010513139.401156466812

Collection:: Naturwissenschaften; Sonstiges

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

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