Pure and applied chemistry: Topological innovation in molecular design: advances in Möbius architectures for functional materials

Hu, Bin; Wang, Dan-Yang; Guo, Yu-Bo; Gong, Han-Yuan

Topological innovation in molecular design: advances in Möbius architectures for functional materials / Hu, Bin (Rights reserved)

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fullscreen: Topological innovation in molecular design: advances in Möbius architectures for functional materials / Hu, Bin (Rights reserved)

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Eingeschränkter Zugang mit Nutzungsbeschränkungen: Das Dokument ist in den Räumen der Zentral- und Landesbibliothek mit dem "Virtuellen Lesesaal der Landesbibliothek" auf allen Internet-Arbeitsplätzen zugreifbar, darf jedoch nicht kopiert, versendet oder in einem Umfang von mehr als 10% ausgedruckt werden. Weitere Informationen.

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Periodical

Title:: Translational Neuroscience

Publication:: Berlin Heidelberg: Springer

Note:: Gesehen am 11.08.15; Open Access; Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International; Archivierung/Langzeitarchivierung gewährleistet

Scope:: Online-Ressource

ISSN:: 2081-6936

ZDB-ID:: 2581219-1

VÖBB-Katalog:: 35425620

Keywords:: Zeitschrift

Classification:: Medizin; Naturwissenschaften

Collection:: Medizin; Naturwissenschaften

Copyright:: Rights reserved

Accessibility:: Eingeschränkter Zugang mit Nutzungsbeschränkungen

Article

Author:: Alahmadi, Adnan; Al-Ghamdi, Jamaan; Tayeb, Haythum O.

Title:: The hidden link: Investigating functional connectivity of rarely explored sub-regions of thalamus and superior temporal gyrus in Schizophrenia

Publication:: Berlin: De Gruyter, 2024

Language:: English

Information:: Abstract: Functional magnetic resonance imaging (fMRI) stands as a pivotal tool in advancing our comprehension of Schizophrenia, offering insights into functional segregations and integrations. Previous investigations employing either task-based or resting-state fMRI primarily focused on large main regions of interest (ROI), revealing the thalamus and superior temporal gyrus (STG) as prominently affected areas. Recent studies, however, unveiled the cytoarchitectural intricacies within these regions, prompting a more nuanced exploration. In this study, resting-state fMRI was conducted on 72 schizophrenic patients and 74 healthy controls to discern whether distinct thalamic nuclei and STG sub-regions exhibit varied functional integrational connectivity to main networks and to identify the most affected sub-regions in Schizophrenia. Employing seed-based analysis, six sub-ROIs – four in the thalamus and two in the STG – were selected. Our findings unveiled heightened positive functional connectivity in Schizophrenic patients, particularly toward the anterior STG (aSTG) and posterior STG (pSTG). Notably, positive connectivity emerged between the medial division of mediodorsal thalamic nuclei (MDm) and the visual network, while increased functional connectivity linked the ventral lateral nucleus of the thalamus with aSTG. This accentuated functional connectivity potentially influences these sub-regions, contributing to dysfunctions and manifesting symptoms such as language and learning difficulties alongside hallucinations. This study underscores the importance of delineating sub-regional dynamics to enhance our understanding of the nuanced neural alterations in Schizophrenia, paving the way for more targeted interventions and therapeutic approaches.

Scope:: Online-Ressource

Note:: Open Access; Archivierung/Langzeitarchivierung gewährleistet

Keywords:: schizophrenia ; fMRI ; functional connectivity ; superior temporal gyrus ; sub-thalamic regions

Classification:: Medizin; Naturwissenschaften; Sonstiges

URN:: urn:nbn:de:101:1-2412131619580.182212713308

Collection:: Medizin; Naturwissenschaften; Sonstiges

Copyright:: CC BY

Accessibility:: Free Access

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