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Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study / Kandukuri, Jayanth (CC BY)

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fullscreen : Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study / Kandukuri, Jayanth (CC BY)

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Periodical

Title:
Innovative surgical sciences
Publication:
Berlin: de Gruyter
Note:
Open Access
Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
Scope:
Online-Ressource
ISSN:
2364-7485
ZDB-ID:
2876075-X ZDB
VÖBB-Katalog:
35278161
Keywords:
Zeitschrift
Classification:
Medizin
Collection:
Medizin
Copyright:
Rights reserved
Accessibility:
Free Access
Title:
Innovative surgical sciences
Publication:
Berlin: de Gruyter
Note:
Open Access
Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
Scope:
Online-Ressource
ISSN:
2364-7485
ZDB-ID:
2876075-X ZDB
VÖBB-Katalog:
35278161
Keywords:
Zeitschrift
Classification:
Medizin
Collection:
Medizin
Copyright:
Rights reserved
Accessibility:
Free Access

Article

Author:
Kandukuri, Jayanth
Jain, Aseem
Karmarkar, Parag
Gadagkar, Hrishikesh
Aberman, Harold
Wang, Qihong
Rege, Abhishek
Title:
Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study
Publication:
Berlin: de Gruyter, 2024
Language:
English
Information:
Objectives: Intraoperative monitoring of blood flow (BF) remains vital to guiding surgical decisions. Here, we report the use of SurgeON™ Blood Flow Monitor (BFM), a prototype system that attaches to surgical microscopes and implements laser speckle contrast imaging (LSCI) to noninvasively obtain and present vascular BF information in real-time within the microscope’s eyepiece. Methods: The ability of SurgeON BFM to monitor BF status during reversible vascular occlusion procedures was investigated in two large animal models: occlusion of saphenous veins in six NZW rabbit hindlimbs and clipping of middle cerebral artery (MCA) branches in four Dorset sheep brain hemispheres. SurgeON BFM acquired, presented, and stored LSCI-based blood flow velocity index (BFVi) data and performed indocyanine green video angiography (ICG-VA) for corroboration. Results: Stored BFVi data were analyzed for each phase: pre-occlusion (baseline), with the vessel occluded (occlusion), and after reversal of occlusion (re-perfusion). In saphenous veins, BFVi relative to baseline reduced to 5.2±3.7 % during occlusion and returned to 102.9±14.9 % during re-perfusion. Unlike ICG-VA, SurgeON BFM was able to monitor reduced BFVi and characterize re-perfusion robustly during five serial occlusion procedures conducted 2–5 min apart on the same vessel. Across four sheep MCA vessels, BFVi reduced to 18.6±7.7 % and returned to 120.1±27.8 % of baseline during occlusion and re-perfusion phases, respectively. Conclusions: SurgeON BFM can noninvasively monitor vascular occlusion status and provide intuitive visualization of BF information in real-time to an operating surgeon. This technology may find application in vascular, plastic, and neurovascular surgery.
Scope:
Online-Ressource
Note:
Open Access
Archivierung/Langzeitarchivierung gewährleistet
Keywords:
blood flow imaging ; real-time feedback ; surgical technology ; noninvasive monitoring ; augmented reality visualization
Classification:
Medizin
Sonstiges
URN:
urn:nbn:de:101:1-2405311537563.957208497356
Collection:
Medizin
Sonstiges
Copyright:
CC BY
Accessibility:
Free Access
Author:
Kandukuri, Jayanth
Jain, Aseem
Karmarkar, Parag
Gadagkar, Hrishikesh
Aberman, Harold
Wang, Qihong
Rege, Abhishek
Title:
Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study
Publication:
Berlin: de Gruyter, 2024
Language:
English
Information:
Objectives: Intraoperative monitoring of blood flow (BF) remains vital to guiding surgical decisions. Here, we report the use of SurgeON™ Blood Flow Monitor (BFM), a prototype system that attaches to surgical microscopes and implements laser speckle contrast imaging (LSCI) to noninvasively obtain and present vascular BF information in real-time within the microscope’s eyepiece. Methods: The ability of SurgeON BFM to monitor BF status during reversible vascular occlusion procedures was investigated in two large animal models: occlusion of saphenous veins in six NZW rabbit hindlimbs and clipping of middle cerebral artery (MCA) branches in four Dorset sheep brain hemispheres. SurgeON BFM acquired, presented, and stored LSCI-based blood flow velocity index (BFVi) data and performed indocyanine green video angiography (ICG-VA) for corroboration. Results: Stored BFVi data were analyzed for each phase: pre-occlusion (baseline), with the vessel occluded (occlusion), and after reversal of occlusion (re-perfusion). In saphenous veins, BFVi relative to baseline reduced to 5.2±3.7 % during occlusion and returned to 102.9±14.9 % during re-perfusion. Unlike ICG-VA, SurgeON BFM was able to monitor reduced BFVi and characterize re-perfusion robustly during five serial occlusion procedures conducted 2–5 min apart on the same vessel. Across four sheep MCA vessels, BFVi reduced to 18.6±7.7 % and returned to 120.1±27.8 % of baseline during occlusion and re-perfusion phases, respectively. Conclusions: SurgeON BFM can noninvasively monitor vascular occlusion status and provide intuitive visualization of BF information in real-time to an operating surgeon. This technology may find application in vascular, plastic, and neurovascular surgery.
Scope:
Online-Ressource
Note:
Open Access
Archivierung/Langzeitarchivierung gewährleistet
Keywords:
blood flow imaging ; real-time feedback ; surgical technology ; noninvasive monitoring ; augmented reality visualization
Classification:
Medizin
Sonstiges
URN:
urn:nbn:de:101:1-2405311537563.957208497356
Collection:
Medizin
Sonstiges
Copyright:
CC BY
Accessibility:
Free Access

Contents

Table of contents

  • Innovative surgical sciences (Rights reserved)
  • ˜Theœ application of robot-assisted microsurgery in orthoplastic surgery / Strübing, Felix (CC BY)
  • Frontmatter (Rights reserved)
  • Who takes the lead in oral surgery simulation? Students’ perceptions and practical skills towards virtual reality and phantom model training: a comparative study / Kröplin, Juliane (CC BY)
  • Frontmatter (Rights reserved)
  • Heterotopic pancreas and malakoplakia in abscessing intrahepatic tumor – a case report / Reschke, Marc A. (CC BY)
  • Correlation of radiographic and histopathological changes with IL-17 and advanced oxidation protein products in knee osteoarthritic individuals with metabolic syndrome / Awan, Uzma Naseer (CC BY)
  • ˜Theœ role of simulation in mastering highly specialized pediatric surgery: current trends and future perspectives / Schuffert, Louisa (CC BY)
  • Current status and future developments in dental implantology – a narrative review / Friedrich, Constanze (CC BY)
  • Recent advances in operative techniques for pancreatic surgery / Strotmann, Johanna (CC BY)
  • Pelvic insufficiency fractures in the elderly – what insights has the past year of research brought? A narrative review / Klepka, Kim Lydia (CC BY)
  • Navigating complexity – how innovation shapes the future of surgery / Drossard, Sabine (CC BY)
  • Frontmatter (Rights reserved)
  • ˜Theœ use of molecular cues to regenerate musculoskeletal tissues / Peniche Silva, Carlos Julio (CC BY)
  • Profiling of inflammatory and anti-inflammatory cytokines in osteomyelitic bone tissue / Lingens, Lara F. (CC BY)
  • Combined inhibition of the complement component C5 and the TLR-coreceptor CD14 alters the posttraumatic response in fracture hematoma in a porcine polytrauma model / Chen, Dong (CC BY)
  • Interdisciplinary lower extremity reconstruction in peripheral artery disease with AV-loops and latissimus dorsi flaps / Reß, Simon (CC BY)
  • Interdisciplinary therapy of extremity soft tissue sarcomas: current evidence on systemic treatments and the role of reconstructive surgery / Steubing, Yonca (CC BY)
  • Interdisciplinary reconstructions of the forearm and hand / Kümmerl, Luca (CC BY)
  • Strategies for surgical reconstruction of complex elbow deformities based on patient-specific instruments – a case series and narrative review / Roth, Sabine Manuela Irene (CC BY)
  • Orthoplastic surgery for interdisciplinary extremity reconstruction / Boos, Anja M. (CC BY)
  • Orthoplastic surgery – regenerative concepts and reconstructive strategies / Beier, Justus P. (CC BY)
  • Frontmatter (Rights reserved)
  • Frontmatter (Rights reserved)
  • Abstracts DGAV (CC BY)
  • Abstracts SCF (CC BY)
  • Abstracts DGU (CC BY)
  • Abstracts DGT (CC BY)
  • ˜Theœ evolving role of esophageal surgery – advancements, challenges, and the path forward / Mönig, Stefan P. (CC BY)
  • Abstracts DGPRÄC (CC BY)
  • Abstracts DGNC (CC BY)
  • Abstracts DGKCH (CC BY)
  • Abstracts DGCH (CC BY)
  • Abstracts DGG (CC BY)
  • Abstracts interdisciplinary (CC BY)
  • Obstacles during training of pregnant doctors in Germany before and after COVID-19: is there a need for change? / Fortmann, Caroline (CC BY)
  • A cross-sectional survey of the safety attitudes questionnaire subscale stress recognition and the effect of non-technical skills training in operating theatre staff / Leuschner, Sebastian (CC BY)
  • Quality of outcome (QoO) in oral cancer patients: prospective perioperative analysis of patients’ resilience and satisfaction during inpatient stay at a University Medical Centre in Germany / Kröplin, Juliane (CC BY)
  • Deep learning for automated boundary detection and segmentation in organ donation photography / Kourounis, Georgios (CC BY)
  • Passage- and serum-dependent changes of adipose-derived stromal cells in vitro: a discrepancy of stemness factors regarding mesenchymal surface markers and expression of stemness-related genes / Sonnenfeld, Renata (CC BY)
  • Conventional partial pancreatoduodenectomy versus an uncinate first, extended partial pancreatoduodenectomy approach for the resection of pancreatic head cancer: the randomized, controlled PancER trial / Heger, Patrick (CC BY)
  • Right hepatectomy in absence of the left portal vein using the porto-rex shunt procedure / Lang, Sven A. (CC BY)
  • Lost in transition? Loss of follow-up and quality of life in adults after resection of choledochal malformation in childhood / Abo-Namous, Reem (CC BY)
  • Learning curves for high tibial osteotomy using patient-specific instrumentation: a case control study / Stimolo, Davide (CC BY)
  • Biological conduits based on spider silk for reconstruction of extended nerve defects / Vogt, Peter M. (CC BY)
  • Current clinical practices of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) / Acs, Miklos (CC BY)
  • ˜Theœ effect of adipose-derived stem cells (ADSC) treatment on kidney histopathological appearance on the Wistar rat models with grade five kidney trauma / Agil, Ahmad (CC BY)
  • Near-infrared indocyanine green angiography in recognizing bowel ischemia in emergency surgery: game changer or overrated? / Christofi, Anastasia (CC BY)
  • Horner syndrome immediately after deep dissection of upper thyroid pole: a case report and review of the literature / Chen, Hongdan (CC BY)
  • Abstracts DGKCH (CC BY)
  • Epigenetic differences in the tumor suppressor genes MLH1 and p16INK4a between Nepalese and Swedish patients with colorectal cancer / Ghimire, Bikal (CC BY)
  • Virtual tumor mapping and margin control with 3-D planning and navigation / Steybe, David Lamaar (CC BY)
  • Abstracts DGAV (CC BY)
  • Depth of intact vascular plexus – visualized with optical coherence tomography – correlates to burn depth in thoracic thermic injuries in children / Dalicho, Valerie (CC BY)
  • Periprosthetic joint infections – a scoping review / Youssef, Yasmin (CC BY)
  • Frontmatter (Rights reserved)
  • Realtime assessment of vascular occlusion and reperfusion in animal models of intraoperative imaging – a pilot study / Kandukuri, Jayanth (CC BY)
  • Is there a role for routine intraoperative cholangiogram in diagnosing CBD stones in patients with normal liver function tests? A prospective study / Lim, Yi Ping (CC BY)
  • Proximal humerus fracture and acromioclavicular joint dislocation / Bieling, Maren (CC BY)
  • Update burn surgery: overview of current multidisciplinary treatment concepts / Schlottmann, Frederik (CC BY)
  • Abstracts DGPRÄC (CC BY)
  • Frontmatter (Rights reserved)
  • Influence of medical didactic training on the self-efficacy and motivation of clinical teachers / Schydlo, Franziska (CC BY)
  • Abstracts Interdisciplinary (CC BY)
  • Frontmatter (Rights reserved)
  • Frontmatter (Rights reserved)
  • What’s new in surgery? Essentials 2024 – young patients and fast decisions / Kröplin, Juliane (CC BY)
  • Abstracts DGCH (CC BY)
  • Abstracts DGT (CC BY)
  • ˜Theœ distribution of robotic surgery in general and visceral surgery departments in Switzerland – a nationwide inquiry / Stalder, Andreas (CC BY)
  • Abstracts DGG (CC BY)
  • Cyanoacrylate vs. sutures in clean and clean-contaminated surgical wounds – a randomised control study / Aravind, Kumkod (CC BY)
  • Early enteral nutrition (EEN) following intestinal anastomosis in pediatric patients – what’s new? / Drossard, Sabine (CC BY)
  • Spontaneous duodenocutaneous fistula: a rare presentation of perforated duodenal ulcer / Barreto, Isabel (CC BY)
  • A narrative review of present knowledge and digital approaches in orthognathic surgery / Friedrich, Constanze (CC BY)
  • A note from the Editor-in-Chief (CC BY)
  • Abstracts Surgical Research (CC BY)
  • Frontmatter (Rights reserved)
  • Best practices and future challenges in the treatment of oral cancer / Kröplin, Juliane (CC BY)
  • Imaging in reconstructive microsurgery – current standards and latest trends / Blank, Beate (CC BY)
  • An update on liver surgery – a new terminology and modern techniques / Tripke, Verena (CC BY)
  • What’s new in surgery – essentials 2023: the ISS young surgeon issue / Kröplin, Juliane (CC BY)
  • From diagnosis to therapy: the acute traumatic hemothorax – an orientation for young surgeons / Rösch, Romina M. (CC BY)
  • IDEAL–compliant implementation of the Dexter ® surgical robot in cholecystectomy: a comprehensive framework and clinical outcomes / Dohmen, Jonas (CC BY)
  • Influence of the COVID-19 pandemic on the amputation rate in Germany in patients with critical limb-threatening ischaemia / Derwich, Wojciech (CC BY)
  • Ileal free flap for hypopharynx reconstruction – case series / Tintinago-Londoño, Luis Fernando (CC BY)
  • Surgical systematic reviews: best available evidence or disposable waste? / Klotz, Rosa (CC BY)
  • Augmented reality and optical navigation assisted orbital surgery: a novel integrated workflow / Tonchev, Nikolay (CC BY)
  • Trastuzumab holds potential to accelerate spontaneous sensory reinnervation after free flap breast reconstruction: a proof of concept / Leskovar, Jana (CC BY)
  • Impact of different parameters on the outcome of vv-ECMO therapy in burn patients – a retrospective cohort study from a burn and high output ECMO center / Bingoel, Alperen S. (CC BY)
  • Registry or randomization – must it be evidence or could it be coincidence? / Radulova, Olga (CC BY)
  • Management of subepithelial esophageal tumors / Schneider, Marcel André (CC BY)
  • Active surveillance in patients with a complete clinical response after neoadjuvant chemoradiotherapy for esophageal- and gastroesophageal junction cancer / Huizer, Tamara J. (CC BY)
  • Neoadjuvant treatment of esophageal cancer: chemotherapy, chemoradiation, immunotherapy, and future trends of therapy / Malekzada, Freschta (CC BY)
  • What is the best surgical approach for esophageal cancer? / Tripke, Verena (CC BY)
  • Immunotherapy as a new perspective for the therapy of esophageal cancer / Huber, Yvonne (CC BY)
  • Oligometastatic disease – a renaissance for surgery? / Goetze, Thorsten (CC BY)
  • Voluminous hiatal hernias – the role of robotic surgery / Dosch, Michel (CC BY)

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